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Audiology in this issue...Genomics
Priya Carling, AuD, Director and Consultant Audiologist, Kent Hearing Ltd, UK. E: priya@Kenthearing.com As a working clinical audiologist, my focus every day is predominantly diagnostics of hearing loss, closely followed by management of ear pathology and rehabilitation of hearing loss...On the influence of sex on tinnitus burden and its phenotypes
One important aspect of the new paradigm in tinnitus research is to question basic assumptions. What associations does the sex of a person have with their experience of and reaction to tinnitus? Chris Cederroth raises the question and tells us...Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours
Introduction Cancer cases continue to increase worldwide, and head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
NSC- HHT – a systematic review of intranasal Bevacizumab
This systematic review of 13 studies concerning the use of an anti-angiogenic nasal treatment in the management of epistaxis in HHT patients finds no significant effect. This paper looked at four RCTs, three prospective studies, three retrospective, one case series...When dinosaurs ruled the earth
Optimism is abundant in medical research, but frequently ends up being tempered with reality. In his inimitable style, Chris Potter looks back over his career – starting with his medical school memories of Bentley-driving ENT consultants, and moving forward through...In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness
Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness
Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...Mind the gap – developing a sustainable pipeline for hearing therapeutics
In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...Where ignorance is bliss, 'tis folly to be wise
Our irrepressible Features Editor, Chris Potter, explores the limits of ignorance. I’m not sure about you, but I seem to exist in a sea of incompetence and ignorance, constantly surrounded by amateurish chumps and feckless underachievers. Now, a lesser man...Nature or nurture in surgical training
It’s Thursday in the UK, so that means time for another root and branch reform of medical training. If you’re not keen on the Greenaway Report (Shape of Training review) [1], don’t fret there’ll be another one along well before...
