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The structure and function of DNA
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...Why does music move us? Music as auditory signals of emotion
Music forms an integral part of the lives of people in all known cultures around the world. In this article Dr Sandra Garrido explains that in fact, our response to music is largely innate and is related to the evolutionary...
Is endoscopic approach more precise in addressing failed ventilation system in chronic mucosal ear disease?
Chronic mucosal disease, as opposed to cholesteatoma, is more directly related to failure of the ventilation system involving three channels. Isthmus anticus and isthmus posticus are channels in front and behind the long process of the incus and there is...Neural plasticity and aural rehabilitation
Neural plasticity refers to an ability of the brain and central nervous system to change their structure and function or their reorganisation in response to environmental cues, experience, learning, behaviour, injury and / or diseases and treatments. Neural plasticity is...OBITUARY: Alan Gibb (1919-2020)
Alan Gibb, who passed away on 5 September aged 101, was the Grand Old Man of British Otology. He slipped quietly away at home on Deeside from the long-term consequences of a stroke about two years ago, from which he...
Outpatient closure of CSF leaks: a good idea or a step too far?
After day-case septoplasty, day case thyroidectomy, now day case CSF leak repair – has the pendulum moved too far? The authors put forward a convincing case for what, only 10 years ago, would have sounded like a provocation. They quote...
Advances in diagnosis and management of allergic rhinitis
This article reviews advances in the diagnosis and management of allergic rhinitis. Recent advances in the diagnosis of allergic rhinitis include testing of local immunoglobulin E (IgE), urinary test to diagnose aspirin hypersensitivity and optical rhinometry to assess degree of...
Allergic rhinitis, the usual suspects
Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...Clinical guidance: using the NAL-NL3 Fitting System in practice
NAL-NL3 modernises hearing aid prescription with modular, evidence-based modules, improving real-world comfort and communication for diverse listening needs. Hearing aid prescription has long relied on a single, audiogram-based formula to guide amplification. While this approach has delivered reliable outcomes for...Current considerations on neural development and hearing loss in young children
The young child’s brain has the ability to change in response to new stimuli, resulting in learning, the foundation of adaptive and intelligent behaviour. For children with hearing loss, a reduction or lack of auditory stimuli can have a ‘lifelong...
