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Eosinophilic complications during dupilumab therapy

4 September 2025 | Richard (Wei Chern) Gan | ENTA - Rhinology / Sinus

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

Virtual and augmented reality in surgery

1 March 2018 | Ivo Dukic | ENTA - ENT

Virtual reality (VR) is a three-dimensional, computer generated environment which can be accessed using a virtual reality headset, allowing individuals to immerse themselves in this virtual world. Augmented reality (AR) systems layer virtual information over a live camera feed into...

Balance and vestibular disorders Issue I

To skip directly to features, click the links below: Welcome from the editor - by Prof Peter Rea How to evaluate and treat the dizzy patient: non-medical diagnosis-based strategies - by Richard E Gans Diagnosis and treatment of BPPV with...

The integration of targeted therapy and surgery in advanced thyroid cancer clinical trials

3 November 2022 | Dan Yaniv, Maria E Cabanillas, Kevin J Contrera, Mark Zafereo | ENTA - Head & Neck

One of the headline speakers, Mark Zafereo, will be talking at IFOS about thyroid cancer. We hear from his team about some of the areas they will be discussing. Locally advanced thyroid cancer generally refers to patients who have significant...

Modernising scientific careers and audiology in the United Kingdom

1 July 2014 | Lizanne Steenkamp | ENTA - Audiology - Adult, ENTA - Audiology - Diagnostic, ENTA - Audiology - Paediatric

Modernising Scientific Careers (MSC) is an education and training strategy for 51 disciplines in healthcare science within the National Health Service (NHS) in the United Kingdom (UK). Some of these disciplines lacked clear training routes as well as registration opportunities...

Trainee-led collaborative research and audit in ENT: where are we now?

1 November 2019 | Matthew E Smith | ENTA - ENT

In late 2015 INTEGRATE, the UK ENT Trainee Research Network, was formed. Since then, two national projects have been completed and INTEGRATE has grown into a larger, more structured organisation, with otology, head and neck and rhinology subcommittees working alongside...

What’s new in genetic testing for hearing impairment?

1 May 2016 | Ali A Danesh | ENTA - Audiology - Diagnostic, ENTA - Audiology - Adult, ENTA - Audiology - Paediatric

Often the first question following the diagnosis of a hearing loss is ‘why?’ In this article Ali Danesh explores the advances made in uncovering ‘why’ from a genetics perspective. Ali describes the panel of genetic tests now commercially available to...

Acute otitis externa: what are the important outcomes?

2 March 2022 | Matthew E Smith | ENTA - Audiology - Adult, ENTA - Otology

Matthew Smith discusses a project looking at outcomes of acute otitis externa interventions, and how, going forward, the INTEGRATE team are working with patients to develop outcome measures. Acute otitis externa (AOE) is one of the most common conditions of...

Surgical management of congenital nasal pyriform aperture stenosis

1 May 2014 | Vikranth Visvanathan, DM Wynne, AW Clement, Kim Ah-See (Prof) | ENTA - Paediatrics, ENTA - Rhinoplasty

Introduction Congenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of neonatal upper airway obstruction which was first described by Douglas in 1952 [1]. The first radiological description of CNPAS was described by Ey et al in 1988 [2]....

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