You searched for "Immunology"
The search for the holy grail of rhinosinusitis: another step towards phenotyping in CRS wNP?
For many years, scientists and clinicians have been trying to understand the infinite variability within the term ‘rhinosinusitis’ using radiology, basic science, epidemiology and then using their insights to solve the riddle of management: how to explain why some patients...
Sinus implants to treat recalcitrant polyps
It is well established that the burden of chronic rhinosinusitis on healthcare costs and patients’ quality of life is high, and that current mainstream treatment options of oral or topical steroids are not without problems. This paper compares two RCTSs...
SNOT-25 to assess CRS - a new tool
The SNOT-22 is a well-established validated instrument, designed to evaluate the rhinosinusitis-specific health status and health-related QOL, however makes only one broad reference to productivity. The objective of this paper is to evaluate a modified SNOT-25 created to better assess...
An alternative view and access point
Fungal sinusitis is a common problem and it is well recognised that it can be difficult to remove all of the fungal matter from the maxillary sinus to ensure no recurrence or residual disease. This study describes a technique utilising...
How to manage the concha bullosa in FESS
It is an interesting concept to assess how much impact the presence of a large concha bullosa (CB) has on both severity of chronic rhinosinusitis (CRS) and also postoperative outcomes after FESS. The authors accept that the paper has limitations...
Potential benefits of turbinate sparing medial maxillectomy
Whilst endoscopic medial maxillectomy (EMM) has good results as the standard treatment option for tumours arising in the maxillary sinus, postoperative problems of crusting, epiphora and paraesthesia are not uncommon. This paper looks at modified EMM aimed at sparing the...
How much does CRS affect Eustachian tube dysfunction symptoms?
We know that chronic rhinosinusitis (CRS) and Eustachian tube dysfunction (ETD) are both very common, and that the two often co-exist but this paper looks to establish the prevalence and severity of ETD in CRS patients, and how much treatment...
A new tool for assessing otoscopy skills
Medical and audiology students need to be proficient in performing otoscopy in order to undertake the routine practice required of them at work upon graduation. One significant challenge in teaching otoscopy is the lack of objective and validated assessment tools...
Location, location, location: How to get the steroid where you need it, in chronic rhinosinusitis
What almost all current guidelines on chronic rhinosinusitis have in common is the importance of intranasal steroid (INCS) use. However, it is increasingly understood that the efficacy of INCS depends on their efficient delivery to the point of need, i.e....
Endoscopic sinus surgery improves Eustachian tube dysfunction
This prospective, multicentre trial from China looked at the improvement in Eustachian tube function after endoscopic sinus surgery. Seventy patients from three tertiary units were included in the study. They all completed the Eustachian tube dysfunction (ETDQ-7) and SNOT-22 questionnaires...
Sinonasal inverting papilloma and HPV - a meta-analysis of recurrent tumours
Sinonasal inverting papilloma (SNIP) is a common benign tumour of the sinuses. Difficulty lies in the association with metachronous or synchronous SCC of the sinus and also in the complete removal of the lesions due to their anatomical location. An...
