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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss
A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...
Alcohol consumption and the risk of developing benign laryngeal disorders?
Alcohol consumption among South Korean adults is apparently high, with over three quarters of the adult population consuming alcohol and a ‘high-risk’ drinking rate of one in five. Excessive alcohol consumption is considered to be a risk factor for developing...
Olfactory ensheathing cells and their safe harvest
This interesting and unique paper not only demonstrates that biopsy of olfactory mucosa in the region of the superior turbinate is a safe procedure but also provides valuable insight into an engaging area of research by a world class team...
Outcome of TORS to tongue base and epiglottis in patients with OSA intolerant of conventional treatment
The use of transoral robotic surgery (TORS) in ENT is rather controversial, but the use of robotic surgery for obstructive sleep apneoa (OSA), makes it doubly so. Previous studies on TORS in OSA have been performed with other types of...
Grading dysphagia as a toxicity in treating head and neck cancer
Common Terminology Criteria for Adverse Events (CTCAE) is a system used by clinicians to grade the toxicity of oncology treatments in a standardised manner. Dysphagia is perhaps the most common long-term toxicity of head and neck cancer treatment. Currently, a...
Experience of the Sophono transcutaneous bone conduction system
This article is a frank discussion of the authors’ experience implanting these devices. The principle of the device is surgical implantation of a bilobed magnet within a bony well in the cranium (similar position to BAHA). The implant is a...
Canal wall down with obliteration of cavity for paediatric cholesteatoma
The authors present evidence that canal wall down (CWD) surgery with primary obliteration is an effective way to treat paediatric cholesteatoma. Fifty-eight ears were operated on and follow-up was for five years on average. Residual cholesteatoma rate was 9.9% with...
Auditory deprivation and single-sided deafness
In cases of bilateral auditory deprivation, there is clear evidence of an inverse relationship between performance after cochlear implantation and the length of severe to profound deafness prior to implantation (i.e. the longer the deprivation the poorer the outcome on...
Impedance for different electrode types
Measuring cochlear implant (CI) electrode impedances is common in CI programming appointments to measure the integrity of the implant e.g. whether there are any open or short electrodes. This is because impedance measures the flow of current between intra and...
