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The MACRO Trial: defining best management of chronic rhinosinusitis

7 January 2026 | Gabija Klyvyte, Carl Philpott (Prof), Claire Hopkins (Prof) | ENTA - Rhinology / Sinus

A major UK trial in The Lancet finds ESS provides greater symptom relief than long-term macrolides for adults with CRS, supporting earlier surgery and fewer antibiotics. The MACRO Programme was established in 2016 when the UK National Institute of Health...