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4538 results found

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...

Lack of early vocabulary growth in bilateral cochlear implant children

Studies indicate that children with unilateral implantation may have delayed vocabulary development for long periods of time even after implantation. This Finnish study attempted to find out whether bilateral cochlear implantation was associated with earlier vocabulary development. The authors analysed...

Swallow assessment: is clinical judgement or objective measurement more reliable?

Swallowing difficulties are life threatening and are the most common referral reason to speech and language therapists working with the adult population. Video fluoroscopic examination is a common instrumental tool used to assist in the assessment of the risk of...

What should be considered a ‘close’ margin in oral cavity squamous cell carcinoma?

Achieving clear margins during surgical resection in oral cavity squamous cell carcinoma (OCSCC) is thought to reduce local recurrence (LR) and improve prognosis; however, what constitutes a clear, close, or involved margin is inconsistent in the literature and in practice....

What is balloon eustachian tuboplasty (BET)?

Eustachian tube dysfunction (ETD) is the result of a combination of factors that interfere with the mucosal functional or cartilaginous structures. Failure to open the eustachian tubes can cause aural pain, pressure in the ears, muffled hearing, crackling/popping sounds in...

A new bio-glue for neurosurgical wound closures

Dural closures need to be tight to prevent cerebrospinal fluid leaks. Traditional wound closure techniques involve sutures and DuraSeal which is the only FDA approved polyglycol hydrogel sealant with proven safety and efficacy profile. This article describes a new sealant,...

Skull base imaging: a review

This excellent review paper describes the anatomy, imaging protocols and differentiating imaging findings on CT and MRI in myriad skull base lesions. Skull base protocol MRI and thin section CT are required to evaluate all skull base lesions. According to...

Above and beyond interprofessional learning

There has been a significant focus on interprofessional education for all health professionals over recent years. The American Speech-Language-Hearing Association became a member of the Interprofessional Education Collaborative (IPEC) competencies (in America) in 2016. These competencies provide four core competencies...

The earlier the better: learning to work together

Working as part of a team can be the most challenging aspect of any health professional’s job role. The authors of this article acknowledge that this is frequently considered a skill that can only be learnt ‘on the job’. Yet...

AM and the neck

Infections with atypical mycobacteria (AM) are increasing, especially with the decline in BCG immunisation. The most frequent presentation is a lymphadenopathy in an immunocompetent child. This poses a difficult diagnostic challenge if the clinician is not aware of this entity....

Paediatric hearing following chemotherapy

This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...