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Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer

The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...

Occlusal splint, injections or arthrocentesis in myofascial pain

Facial pain is a fairly common complaint and may present in a myriad of symptoms. These patients present to both dentists and general practitioners and could end up referred to a number of specialists. Temporomandibular disorders may originate from either...

CRSwNP, another monoclonal antibody

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...

Standardising videofluoroscopy assessment for bottle-fed babies

Swallowing problems in babies may occur for many reasons including complex medical problems, premature birth, and low birth-weight. Dysphagia causes several further morbidities such as poor nutrition and compromised respiration, often raising distress for both infants and their caregivers. Early...

A single blinded RCT comparing triamcinolone with 5-FU treatment for keloid scars

This single blinded RCT compared 43 patients with 50 symptomatic keloids that were randomised to two matched groups of 25 scars, receiving either 5-fluorouracil (5-FU) or current first line treatment, triamcinolone (TAC). The surgeon administering the injectable treatments was unblinded,...

Cocaine detection hours after FESS

This is a very interesting article from Australia regarding the bioavailability of cocaine following atomised application prior to endoscopic sinus surgery. The well-established practice of preparing the nasal mucosa for sinus surgery involves the placement of a usually modified Moffett’s...

Nasal physiology and septal perforations

This interesting article from North Carolina and New York aims to assess the impact of anterior septal perforations on nasal physiology, using computational fluid dynamics and computer simulation. A computerised 3D model was constructed of a normal patient aged 37,...

The effects of polypharmacy in the elderly

Another pill to cure the ill? Alec Lapira discusses the warning signs of polypharmacy in the elderly population. Polypharmacy in the elderly Polypharmacy – defined as the use of five or more medications – occurs in 20–37% of older people...

In conversation with Chadwan Al Yaghchi - Cutting Edge Laryngology 2019

Chadwan Al Yaghchi is a founding member of the British Laryngological Association and served on the council since 2013. He is currently the associate honorary treasurer. How did the idea for Cutting Edge Laryngology come about? 2010 was a time...

BAAP Hallpike Prize - Application Deadline 1st January 2020

BAAP Hallpike Prize The Hallpike prize was first awarded in 2009, following the kind donation of Dr Jeremy Hallpike, Emeritus Neurologist from Adelaide, Australia, in honour of his father Charles Skinner Hallpike. The prize is awarded annually for the best...

Do you treat RRP?

Do you treat RRP? Please join the national Airway Intervention Registry: Recurrent Respiratory Papillomatosis (AIR: RRP) online database. This is a unique opportunity to contribute to a collaborative, UK-wide study collecting real world data on treatments for this rare but...

Global CI Collaborative: Futures Forum - Webinar Series

The Global CI Collaborative presents a five-part global leadership webinar series that will explore the future of cochlear implantation following the global pandemic.