You searched for "adjuvant"
RCT: tongue retaining devices vs CPAP for OSA
This study compared the effect of a tongue retaining device versus the use of CPAP in 27 patients within a crossover RCT design. Tongue retaining devices (also known as tongue stabilising devices), are similar in appearance to a plastic tongue-sized...
Multiple surgeries for RRP – does a greater number of operations result in a worse voice outcome?
Recurrent respiratory papillomatosis (RRP) of the larynx remains a challenging condition to treat, with a number of affected patients requiring multiple operations to remove recurrent disease over the course of their lifetime. At the most severe end of the spectrum,...
Reducing the risk of Frey’s syndrome after parotidectomy – which methods are best?
Gustatory sweating or Frey’s syndrome is a well-recognised complication of parotid surgery. The reported incidence is highly variable, from 4% to 96%, with around 30% of patients reporting symptoms. A number of intraoperative techniques can be used to reduce the...
Predicting the nature of swallowing deficits caused by surgical resection of the tongue?
Patients treated surgically for cancer of the tongue are expected to have difficulty in eating, drinking and swallowing. The authors of this paper report on a cohort of 106 patients in their practice who had surgical resection as primary treatment....
Extracapsular dissection alone for low-grade malignancies of the parotid gland – oncologically sound?
The general treatment strategy advocated for a primary carcinoma of the parotid gland is surgical resection +/- adjuvant radiotherapy. A selective neck dissection is usually recommended in all cases of parotid malignancies, except for small, low-grade tumours. In this paper,...
A systematic review of adjunctive probiotic therapy in the management of chronic rhinosinusitis
It is generally understood that administering substances containing live microbiologically active micro-organisms (probiotics) enhances the treatment of chronic rhinosinusitis. Probiotics manipulate and rebalance the alterations occurring in the local microbiome in chronic rhinosinusitis patients. This results in propagation of healthy...
Should we reconsider induction chemotherapy in advanced stage laryngeal cancer?
Use of chemo-radiotherapy for advanced laryngeal cancer led to a major shift in treatment as an alternative to total laryngectomy. Despite widespread adoption of chemoradiotherapy, survival rates have not improved and the original premise of matching neoadjuvant chemotherapy tumour response...
Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...
Intraoperative identification of primary tumours in unknown primary head and neck cancer using transoral laser microsurgery with frozen sections
The aim of the study was to compare the sensitivity and specificity of intraoperative identification of primary tumours in patients with unknown primary head and neck squamous cell carcinoma (UP HNSCC) using transoral laser microsurgery (TLM) with frozen sections, with...
