You searched for "trial"

1421 results found

Review: Cochlear Implantation in SSD?

Contra lateral routing of signals (CROS) using hearing aids and bone conduction devices has been the conventionally accepted modality for the treatment of single sided hearing impairment. The CROS hearing aid has been found to improve speech understanding in noise,...

How can we improve outcomes for patients with acute vestibular neuritis?

Vestibular neuritis is a common disorder that can leave up to 50% of patients with persistent vertigo symptoms for months to years following the acute insult. Often their first contact with ENT or balance specialists is many months after the...

Vascular vertigo and dizziness: diagnostic criteria

This diagnostic criteria is one of the latest produced by The Bárány Society. It is a useful addition to previous ones for vestibular disorders. Vascular vertigo/dizziness by definition is caused by stroke, transient ischaemic attack (TIA), isolated labyrinthine infarction/haemorrhage and...

Saline irrigation in CRSwNP after surgery

This article, largely from Germany, aims to prove the effectiveness of nasal saline irrigation in postoperative patients with CRS with nasal polyps. A prospective, single blinded randomised trial was designed with an irrigation and non-irrigation arm. Patients who underwent sinonasal...

Day care stapes surgery

This paper reports on a proposed unblinded, randomised controlled trial in which the hearing outcomes after inpatient stapes surgery will be compared with those after day case stapes surgery. The study is currently in the recruitment stage and plans to...

The evidence for various treatments of autoimmune ear disease

The difficulty with this disease entity is that it is a heterogeneous group of conditions affecting the ear and a widely accepted diagnostic criteria does not exist. It is therefore difficult to conduct a well controlled trial and this systematic...

Anticoagulated patients and epistaxis

This systematic review looks at the increasing complexity in this space as anti-thrombotics become more sophisticated and move away from the more well understood management of warfarinised patients. After a thorough search, 29 papers were found to be relevant and...

Eosinophilic complications during dupilumab therapy

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

The stubborn polyp cases are ‘different’

The widely different behaviour of nasal polyp disease between patients is a major feature of rhinology practice and makes counselling of patients difficult when approaching their first operative intervention. Setting aside aspirin sensitivity (Samter’s triad), which is known to be...

Patient factors associated with spontaneous CSF leak

This article highlights the role of obesity, sleep apnoea and raised intracranial pressure as linked pathologies in the aetiology of the spontaneous cerebrospinal fluid (sCSF) leak. The authors link sCSF leak with obesity and comment on sCSF leak incidence increasing...

Honey in the management of mucositis

This is a meta-analysis of randomised controlled trials. Despite some limitations, they were able to identify that honey could reduce the severity of radio/chemotherapy induced oral mucositis. They acknowledge that the exact aetiology in the effect of honey is not...

Patient and public involvement in research

One step further from involving patients in setting research priorities is to involve them in the planning and recruitment stages of the subsequent trials and studies. Here, Carl Philpott and Aneeka Degun explain the concept of Patient and Public Involvement...