A 3D-printed endoscopic sinus surgery simulator – validity testing

The challenge of gaining sufficient experiential learning to successfully navigate the learning curve toward competence has long been a challenge in surgical education. The COVID-19 pandemic, and its impact on elective capacity, has presented a further challenge to the acquisition...

Predictors of diabetes insipidus post-hypophysectomy

Transient diabetes insipidus (DI) after pituitary surgery is not uncommon and its diagnosis fairly obvious. Permanent DI is rare and often depends on the neurosurgeon’s experience. This retrospective study describes a large series of patients with majority undergoing endoscopic transsphenoidal...

OSA is neuroprotective!

This interesting study supports the hypothesis of the protective effects of obstructive sleep apnoea (OSA) against ischemic events like stroke. The authors evaluated the impact of OSA with the presentation, hospital course and outcomes of patients with subarachnoid haemorrhage (SAH)....

One airway, one disease - not for everyone!

While 85% of asthmatic patients have rhinitis, only 20-30% with rhinitis have asthma. Together with atopic dermatitis (AD), rhinitis and asthma form a triad that tend to co-exist in patients (multimorbidity). This co-existence raises the possibility of genetic mechanism. Authors...

Can we avoid FESS in patients with true isolated odontogenic sinusitis?

This is a useful study looking at how best to manage patients with odontogenic sinusitis and if FESS can be safely avoided. The authors treated patients by removing the odontogenic cause of the rhinosinusitis by extracting the offending tooth and...

Earlier intervention to correct anosmia?

This is an interesting study aimed to determine the timing for successful surgical intervention in improving the sense of smell in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). A total of 86 CRSwNP patients with loss of smell and...

Persistent symptoms of smell loss after COVID-19 infection

Anosmia as a result of COVID-19 infection is well recognised. This timely and topical French paper looks at 115 patients with proven SARS-CoV-2 infection, who were contacted with specific questions about olfactory and gustatory disturbance. They found 81% of patients...

PET-CT for malignant nasopharyngeal lesions

This retrospective Turkish review of 92 patients aimed to determine the ability of fluorine 18-fluorodeoxyglucose (FDG) maximum standardised uptake value (SUVmax) on positron emission tomography/computerised tomography (PET/CT) to differentiate benign processes and malignant nasopharyngeal lesions. The authors retrospectively reviewed the...

Dupilumab prospective RCT for CRSwNP, a multinational trial of 60 patients with a 16-week CT follow-up

This transcontinental work describes a randomised, double blind, placebo controlled parallel group study over a 16-week period, assessing 60 patients with CRSwNP by CT scan scores. All patients had a four-week period of intranasal corticosteroids followed by randomisation to add...

An objective office-based method for diagnosing allergic rhinitis

There are several signs of allergic rhinitis which, helped with skin prick and blood tests, can diagnose the problem. However, an endoscopic, on-the-spot test may surmount clinical uncertainties and invasive testing to acquire the same goal. In this study, the...

Those little friends in our noses

Human microbiota plays an important role in both health and disease including metabolism, immunomodulation, and a potential role in chronic inflammatory conditions such as chronic rhinosinusitis (CRS). The authors aimed to investigate the sinonasal microbiome using 16S rRNA gene sequencing...

Eustachian tube dysfunction usually improves following endoscopic sinus surgery

This study investigated effects of endoscopic sinus surgery (ESS) on eustachian tube dysfunction (ETD) and factors associated with improvement. This was a retrospective study which included 302 patients over 17 years old who underwent ESS between 1 December 2016 and...