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Discovery in the genetics of complex disease: Otitis media
Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...
Temperature-controlled radiofrequency treatment of the nasal valve confers sustained benefit
Aiming to investigate long-term efficacy and safety (three years post treatment), this was an extension of a previous multicentre, prospective, single-blinded, randomised controlled trial that investigated the effectiveness and safety of temperature-controlled radiofrequency treatment (TCRF) to the nasal valve (NV)...
Patients with severe uncontrolled CRSwNP respond to biologics in the real world
Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...A funny thing happened on the way to a conference – and other stories
This series of stories is dedicated to those of you with whom some of these moments were shared (or endured) and, above all, to my amazing and long-suffering husband, David Howard. Most of you know him as an exceptional head...Are noise-cancelling headphones a cause for concern?
Audiologists are calling for more research into the impact of noise-cancelling headphones on auditory processing, particularly among children and young people. The issue has been receiving media attention recently after a BBC News report asked whether headphones are to blame...
Identifying congenital CMV: the screening debate
Congenital cytomegalovirus (cCMV) is a significant global public health burden and is the biggest non-genetic cause of childhood hearing loss, as well as being an important cause of neurodevelopmental delay. Despite a study concluding that there was not enough evidence...
TMJ arthrocentesis
This is a paper from Brazil where they attempted to clarify the volume required for an arthrocentesis to the temporomandibular joint. Nineteen cadavers had methylene blue injected into the upper joint space. Conventional arthrocentesis was then conducted with 300ml of...
Review of surgical treatments of intractable Meniere’s disease
This is a nice summary of the evidence available for the surgical treatments for intractable Meniere’s disease. To summarise, in five-10 years, over 90% of vestibular neurectomy cases, more than 80% of intratympanic gentamycin treatment, and 70-80% of endolymphatic sac...
What is in the Fountain of Youth?
Does the auditory system have to age? Can we become more like turtles or jellyfish and keep our internals running without degradation? This essay considers the theoretical underpinnings of biological processes in the cochlear, in particular the role of the...
Metaplasia of the concave septum
This group conducted a one year prospective study and sampled mucosa from 42 randomly selected patients with septal deviation at a single centre. They found significantly higher rate of squamous metaplasia and lymphocytic infiltration in septal mucosa on the concave...
Keep the condyle if you can
This is a study of 41 patients who underwent benign tumour resection and reconstruction over a four year period. Patients fell into three groups; condyle preserved, condyle sacrificed, condyle frozen in combination with a DCIA free flap. Following this, they...
