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1755 results found

An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer

Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...

Modifying two-week wait protocol for suspected head and neck cancer patients during COVID-19

As healthcare workers, we are committed to ensuring that our patients continue to receive the optimum care that we are set up to deliver. However, the last year has shown that we need to be mindful of balancing this with...

Can we predict risk of adverse events preoperatively in patients undergoing head and neck cancer surgery?

Ed’s Choice reviews a paper aiming to create a reliable index to predict postoperative outcomes in head and neck cancer patients. This interesting study identifies variables that may assist in risk assessing prospective surgical candidates. There have been a few...

Does transoral robotic surgery improve outcomes among patients with head and neck cancer of unknown primary?

A tonsillectomy and tongue base mucosectomy is becoming increasingly accepted as the optimal surgical intervention to aid in identifying the primary source of a p16+ / HPV-related squamous cell carcinoma (SCC) of unknown origin, given that this disease almost exclusively...

Less pain more gain: impact of prophylactic gabapentin on swallowing outcomes in head and neck cancer patients undergoing radiation treatment

Patients planned for chemoradiation to the head and neck are usually advised to expect some pain and soreness during their treatment and that pain relief will be offered as and when it is required. Uncontrolled pain and mucositis affect oral...

How do objective ratings of swallowing compare with patient-reported dysphagia QOL measures in the head and neck cancer population?

Swallowing may be assessed by a comprehensive battery of tools including instrumental/objective assessments, clinician-rated measures and patient-reported measures. The authors of this paper use secondary analysis to explore concordance between videofluoroscopy and a patient-reported dysphagia quality of life (QOL) measure....

T1 lip cancer and cervical lymph node metastases

The management of large lip squamous cell carcinoma (SCC) (T2, T3, T4 tumours) or those with nodal disease is well established. However the management of T1N0 tumours is controversial due to the assumed low risk of occult lymph node metastases....

KTP laser ablation for early glottic cancer

TLM for glottic carcinoma has historically been performed with a carbon dioxide (CO2) laser. A much smaller literature base has examined the use of potassium titanyl phosphate (KTP) laser in this context. This retrospective chart review aims to fill that...

Smoking causes cancer – so what’s new?

You may well ask what is the novel value of a paper looking at smoking habits in patients with confirmed head and neck squamous cell carcinoma (HNSCC), but this paper highlights some pertinent points for clinical practice in the current...

The first major NHS cancer case performed at HCA London Bridge Hospital Cancer Centre

In the words of Mr Jean - Pierre Jeannon, 'we will get through this together'. Never better demonstrated than through the life saving team work seen yesterday led by JP and Mr Ricard Simo...CLICK HERE

Postoperative radiation in early stage oropharyngeal squamous cell cancer (OPSCC)

There is significant variation in treatment strategies for OPSCC between units. This is largely due to unanswered questions which continue to exist beyond the published literature. We know that human papilloma virus status has a significant influence on prognosis but...

Is dissection of level IV necessary in patients with negative neck oral cancer?

Supraomohyoid neck dissection (SOHND) refers to the removal of lymph nodes contained in levels I-III and is currently referred to as a selective neck dissection levels I-III. This type of neck dissection has been frequently used in the management of...