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Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...


Asymmetrical hearing loss following prolonged occupational noise exposure

Noise-induced hearing loss (NIHL) is one of the commonest occupational conditions and has been linked with increased risk of work-related injuries. Noise-induced hearing loss is traditionally associated with bilateral symmetrical sensorineural hearing loss unless they are exposed to unilateral noises,...


Transmastoid facial nerve decompression for persistent traumatic facial nerve paralysis

Facial nerve paralysis (FNP) can occur following trauma, with a small number of these patients requiring facial nerve decompression (FND) to aid recovery. The authors shared their experience in decompressing the facial nerve for persistent severe FNP via a transmastoid...