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Stem cells in nasal polyposis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is common and is multifactorial with increased T-helper 2 response and active role of interleukin 5. It can be associated with asthma and control of CRSwNP improves lower airway disease. Due to constant cellular...
A new biomarker for chronic rhinosinusitis
This Chinese study looked at the feasibility of periostin (usually found in bone and lung tissue) as a biomarker for chronic rhinosinusitis. They sampled ethmoid mucosa in 12 patients with chronic rhinosinusitis without nasal polyposis (CRSsNP) and 25 patients with...
Risk factors for post tonsillectomy bleeds
This paper reviews post-tonsillectomy bleeding in 692 patients and attempts to tease out risk factors. The overall bleed rate of 11.6% seems very high. The return to theatre rate was 2.6%. The paper identifies male patients and adult patients as...
Biopsy sites with a diagnosis of pemphigusand mucous membrane pemphigoid
This is a systemic review and met-analysis to critically evaluate optimal biopsy site for patients presenting with pemphigus or mucous membrane pemphigoid. Historically, diagnosis is made if H&E staining direct immunofluorescence and serological testing of auto-antibodies. Direct immunofluorescence has been...Drug side-effects on audiological and vestibular testing
Are they a malingerer? Or perhaps they are inattentive? It may be their drugs! Robert DiSogra considers the side-effects of medication on the test subject. The audiogram serves many purposes in clinical practice. For the audiologist, it helps to differentiate...
Safety factors in use of balloon tuboplasty
Various medications used to restore eustachian tube function have unpredictable results and these are often disappointing. Balloon dilatation of eustachian tube came around 2010 but has not really gained momentum, mainly due to apprehended complications. In this review article, the...The Brain’s Connectome – a symphony inside our brains and how hearing loss disturbs the music
Understand us; where do we begin? In this article the authors’ introduce a project that may uncover that our personalities and traits are a product of the interconnected wiring within our brain. The team discusses the Human Connectome Project and...
