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IL-25 and nasal polyps, another target
Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...
What should be considered a ‘close’ margin in oral cavity squamous cell carcinoma?
Achieving clear margins during surgical resection in oral cavity squamous cell carcinoma (OCSCC) is thought to reduce local recurrence (LR) and improve prognosis; however, what constitutes a clear, close, or involved margin is inconsistent in the literature and in practice....
A new bio-glue for neurosurgical wound closures
Dural closures need to be tight to prevent cerebrospinal fluid leaks. Traditional wound closure techniques involve sutures and DuraSeal which is the only FDA approved polyglycol hydrogel sealant with proven safety and efficacy profile. This article describes a new sealant,...
The earlier the better: learning to work together
Working as part of a team can be the most challenging aspect of any health professional’s job role. The authors of this article acknowledge that this is frequently considered a skill that can only be learnt ‘on the job’. Yet...
Factors affecting compliance of follow-up of patients with chronic otitis media
Patients with retraction pockets and small cholesteatomas need good surveillance as well as those surgically treated for cholesteatomas. This is particularly important in closed techniques where a second look or diffusion weighted MRI can pick up any recurrence or residual...
Chronic rhinosinusitis and sleep
This is an interesting article from the Chung Shan Medical University in Taiwan. One-hundred-and-thirty-nine patients were enrolled into this five-year study. They all had chronic rhinosinusitis with or without polyposis and underwent sinus surgery. The aim was to investigate a...
Implantable devices and large magnets – do they mix well?
Although all brands are MRI safe at 1.5 T, the active middle ear implant system Vibrant Soundbridge (VSB), is special since it houses two magnets. These include a magnetic floating mass transducer (FMT) and an audioprocessor fixing receiver magnet which...
A spoonful of sugar… helps the operated sinuses calm down?
Ottoviano et al. present a prospective double-blinded RCT to assess the effect of a nasal gel containing silver sucrose octasulfate (Silsos Gel) on wound healing after endoscopic sinus surgery. The placebo used was a glycol gel. Thirty-four consecutive patients were...
Risk factors for post laryngectomy fistula
This is a meta-analysis looking at the postoperative pharyngocutaneous fistula rates following total laryngectomy. The authors ended up with 34 studies with about 2500 patients. The most striking finding was that preoperative radiotherapy was a significant risk factor as well...
Novel balloon device to control cavernous sinus bleeding
In their Letter to the Editor, the authors suggest a draft for a novel balloon catheter device for sinus haemostasis during trans-sphenoidal surgery which is associated with uncontrollable sinus bleeding in 1-8% cases. Their proposed device has a single lumen...
Surgery for hypopharyngeal obstruction causing OSA
Surgical treatments for OSA are evolving with improved diagnostic accuracy of the level(s) involved. Where the collapsing segment lies below the soft palate, a variety of surgical techniques to correct the affected segment(s) are emerging. This article concentrates on one...
