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‘Dead ear’ after mastoid surgery
The primary aim of surgery in the management of cholesteatoma is eradication of the disease which can potentially result in serious complications such as intracranial extension, facial nerve weakness and further hearing loss. A profound hearing loss resulting postoperatively considerably...
Allergic rhinitis, the usual suspects
Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...
Immunosuppresants and ototoxicity
There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...Minimise waiting times with Peptest!
In laryngopharyngeal reflux (LPR), refluxed stomach contents travel up the oesophagus and reach the larynx, causing chronic extra-gastrointestinal symptoms such as a persistent cough, hoarseness or difficulty swallowing, meaning it is often attributed to ENT problems.Supporting the definitive diagnosis of LPR
Voice disorders affect one in 25 people in the UK, and laryngopharyngeal reflux (LPR) is a common culprit. LPR occurs when the stomach contents – including strong digestive enzymes like pepsin – flow back up into the throat, causing inflammation...Clinical and financial success by providing specialised audiological tinnitus management
Diagnosis and management of a patient with chronic subjective tinnitus is one of the most labour-intensive areas of hearing healthcare. This is one reason some hearing care providers opt to exclude specialised tinnitus care from their practice: it may not...Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour
Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...In conversation with Professor Patrick Gullane: My life in Otolaryngology-Head & Neck Surgery
Fellowship RCSEng 2009. Patrick, as you have recently ‘stepped down’ as Chairman and Chief of ORL-HNS at Toronto General Hospital, what next? Firstly, so often I have been asked why I selected this career path, from a quote by Johnny...Innovative approaches to treating deafness
Shahar Taiber and Karen Avraham give us a summary of gene therapies for hearing loss, with an overview of limitations and what the future holds. Hearing loss is the most common sensory disorder. The last two decades have seen a...Academic Achievement Award for De Wet Swanepoel
Congratulations to Daniël Christiaan De Wet Swanepoel for being one of the recipients of the University of Pretoria’s 2023 Academic Achievement Awards.
