Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

SEQaBOO: SEQuencing a Baby for an Optimal Outcome

There are at least 15 countries now running genome sequencing projects. The team in Manchester, UK, and Boston, USA, share their SEQaBOO project. Abstract SEQaBOO (SEQuencing a Baby for an Optimal Outcome) will transform newborn hearing screening (NBHS) by bringing...

Innovative approaches to treating deafness

Shahar Taiber and Karen Avraham give us a summary of gene therapies for hearing loss, with an overview of limitations and what the future holds. Hearing loss is the most common sensory disorder. The last two decades have seen a...

Mobile technologies to support global ear and hearing care

By combining mobile technology with artificial intelligence, more people can access ear and hearing care. The World Health Organization (WHO) estimates that worldwide, nearly half a billion people have moderate or worse hearing loss [1]. The vast majority of people...

Using tele-audiology in Zambia’s ear and hearing care desert

Addressing the medical desert with tele-audiology and tele-education. If a ‘medical desert’ is defined as a community that lives more than 60 miles away from the nearest acute care hospital, then try to imagine an appropriate term for a situation...

Differing outcomes of three Sub-Saharan Africa journeys with the common goal of task sharing in audiology

Task sharing can be designed and implemented specific to the needs of each programme. Foundational principles of global health include developing local leadership as a means to successful sustainable service provision in low- and middle-income countries (LMIC) or regions. It...

Barrier and opportunities for hearing care: finding a way forward for all

Ideal models of care for communities can include tailored ear and hearing care interventions. Barriers exist at an individual and societal level to realise the vision of hearing care for all, regardless of country or resource setting. Affordability of hearing...

Unpacking the World Health Organization’s World Report on Hearing: what does it say?

The inaugural report on hearing from the World Health Organisation is a tool for advocacy, and for getting hearing loss on government agendas. Nguyen Ngoc Bao Tran was 11 months old when her hearing loss was diagnosed. Despite being informed...

Outreach to build capacity for surgical ear care in low-resource settings: challenges and opportunities

There are successful models for delivering complex ear surgery where resources may be more limited. Ear, nose and throat conditions are frequently overlooked when global health issues are considered, but hearing loss is the world’s most common sensory deficit, and...

Promoting human rights of deaf communities in low-resource settings

Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...

Mapping the financial and disease burden of hearing loss and associated interventions

The prevalence and burden of ear and hearing disorders is huge and, historically, has been underappreciated. Globally, unaddressed hearing loss poses a growing public health challenge, requiring urgent attention from policymakers, health professionals and civil society. The recently published World...

Bringing ear care and hearing services to the hardest to reach: the potential of primary healthcare workers

Can workers from the local community plug the workforce gap in providing ear and hearing care? Bringing ear and hearing care services closer to the community remains a key component of reducing the burden of ear and hearing conditions across...