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American Journal of Rhinology & Allergy cover image.

The future of biologics?

3 July 2023 | | ENTA - Maxillofacial Surgery, ENTA - Rhinology / Sinus
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...
EUROPEAN ARCHIVES OF OTORHINOLARYNGOLOGY cover

Organoids in otolaryngology

4 March 2024 | | ENTA - ENT, ENTA - Rhinology / Sinus | 3D tissue model, Organoids, Otolaryngology—head and neck surgery, Stem cells, Tumor prediction model
This interesting review article summarises the status as well as future prospects of organoid technology in our field. Organoids are a mass of cells which are typically cultured in vitro with 3D technology. They simulate miniature tissues and organs and...
EUROPEAN ARCHIVES OF OTORHINOLARYNGOLOGY cover

ChatGPT to select patients for biologic therapies in CRSwNP?

3 May 2024 | | ENTA - Rhinology / Sinus
This short communication describes programming the artificial intelligence (AI) algorithm for systematic review of current literature about guidelines on the clinical efficacy and safety of biologics in the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP). The authors first performed...
Oto Rhino Laryngology journal cover image.

Elevated intracranial pressure versus migraines versus sinusitis?

4 November 2025 | | ENTA - Neurotology, ENTA - Otology
This narrative review discusses the challenges faced by an otolaryngologist to differentiate elevated intracranial pressure (eICP), migraines and chronic rhinosinusitis (CRS). Facial pain, pressure, aural fullness, muffled hearing and tinnitus are often common symptoms described by patients with all three...

Harnessing head and neck cancer genomics for personalised medicine

1 March 2016 | | ENTA - Head & Neck
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Gene therapy restores baby’s hearing

31 May 2024
The guest editor of a forthcoming supplement for ENT & Audiology News has helped enable a baby girl born deaf to hear unaided for the first time.

Endotypes in chronic rhinosinusitis: clinical relevance

3 May 2024 | | ENTA - Rhinology / Sinus
Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

Prof ED Kitcher

1 September 2019 | | ENTA - ENT
Much has been said of the paucity of ENT Services in Africa [1]. Whilst Ghana has always been at the forefront of healthcare in Sub Saharan Africa, its ENT and allied services were somewhat suboptimal in the 1980s. This article,...

Supporting music listening through cochlear implant services – experience from a UK adult clinic on supporting musical engagement

3 September 2021 | | ENTA - Audiology - Auditory Implants, ENTA - Otology
The perception and enjoyment of music is central to many people’s lives. Harriet Crook (herself a cochlear implant recipient) tells us about important work in this area for people using hearing aids and CIs. There is now a wealth of...

Differing outcomes of three Sub-Saharan Africa journeys with the common goal of task sharing in audiology

4 May 2021 | | ENTA - Audiology - Adult, ENTA - Otology
Task sharing can be designed and implemented specific to the needs of each programme. Foundational principles of global health include developing local leadership as a means to successful sustainable service provision in low- and middle-income countries (LMIC) or regions. It...

Specialist teams deliver world-class trauma care

1 July 2014 | | ENTA - General
University Hospitals Birmingham NHS Foundation Trust runs the Queen Elizabeth Hospital Birmingham, which is a designated Major Trauma Centre. The Trust holds the contract to treat all UK injured military personnel evacuated from combat zones overseas. More than 1200 of...

Singing after laryngectomy: Shout at Cancer

1 September 2016 | | ENTA - Laryngology / Swallowing / Voice
Thomas Moors is an ENT junior doctor with a background in music and singing. Combining these interests, he has set up a charity to help patients who have had a laryngectomy. He has achieved considerable public attention, and he tells...