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Expanding the role of FNA in thyroid nodule decision-making
Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...
Posturography in persistent postural-perceptual dizziness (PPPD)
Those in neuro-otology practice will be familiar with PPPD now appearing in the forthcoming beta edition of ICD-11. This condition combines the symptoms of phobic postural vertigo and chronic subjective dizziness in which anxiety plays a part. The underlying hypothesis...
Alcohol consumption and the risk of developing benign laryngeal disorders?
Alcohol consumption among South Korean adults is apparently high, with over three quarters of the adult population consuming alcohol and a ‘high-risk’ drinking rate of one in five. Excessive alcohol consumption is considered to be a risk factor for developing...
Differing types of pharyngeal pouch
This article raised an eyebrow on the grounds that apparently more than one type of pharyngeal pouch exists! They differ in terms of aetiology, site and approach to treatment, therefore awareness of them is advised to ensure the appropriate surgical...
Is the lack of sunshine the reason behind allergic rhinitis?
Deficiency in Vitamin D, an in vogue immunomodulator, has been shown in emerging data to have a substantial pathogenetic role in allergic related diseases, particularly asthma. The concept of a shared upper and lower airway has allowed the natural extrapolation...
Olfactory ensheathing cells and their safe harvest
This interesting and unique paper not only demonstrates that biopsy of olfactory mucosa in the region of the superior turbinate is a safe procedure but also provides valuable insight into an engaging area of research by a world class team...
Speech and language therapy is valuable for people at all stages of dementia
The number of people living with dementia is going to increase significantly over the coming 10-20 years. The authors of this article describe the breadth of the role of speech and language therapists (SLTs) working with people with dementia. They...
Role of oral and intranasal steroids in the management of otitis media with effusion
Inflammation is considered an important factor in the pathogenesis and continuation of otitis media with effusion. Theoretically, this may support the use of steroids, oral or intranasal in the management of this condition. This study comprised three well matched groups...
Stem cells in nasal polyposis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is common and is multifactorial with increased T-helper 2 response and active role of interleukin 5. It can be associated with asthma and control of CRSwNP improves lower airway disease. Due to constant cellular...
A mouth-rinse test that can screen for oral cancer?
This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...
What is the evidence for duration of antibiotic prophylaxis in head and neck free-flap cases?
The topic of this systematic review is one which is commonly heard in discussions between microbiologists and head and neck surgeons – what is the evidence for antibiotic prophylaxis in clean-contaminated free-flap cases, and crucially, how long should antibiotics be...
