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External auditory canal carcinoma
Although uncommon, primary malignant tumours of the external auditory canal (EAC) are associated with a poor prognosis as they often present late. In this study the authors evaluate the clinical and pathological factors associated with treatment and outcome of EAC...
Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...
Predicting the need for salvage laryngectomy
The treatment of laryngeal cancer has seen a shift towards organ preservation strategies with non-surgical treatment offering equivalent survival outcomes. Nonetheless, salvage total laryngectomy (SLT) remains an important curative management option in cases of treatment failure or recurrence. The authors...
Does transoral robotic surgery improve outcomes among patients with head and neck cancer of unknown primary?
A tonsillectomy and tongue base mucosectomy is becoming increasingly accepted as the optimal surgical intervention to aid in identifying the primary source of a p16+ / HPV-related squamous cell carcinoma (SCC) of unknown origin, given that this disease almost exclusively...
Adjuvant radiotherapy for T4N0 laryngeal cancers treated with laryngectomy
A total laryngectomy remains the gold standard for the initial treatment of advanced (T4) squamous cell carcinomas of the larynx without evidence of distant disease. Adjuvant radiotherapy (RT) is also recommended for such cancers. In the absence of other adverse...
Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?
Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...A funny thing happened on the way to a conference – and other stories
This series of stories is dedicated to those of you with whom some of these moments were shared (or endured) and, above all, to my amazing and long-suffering husband, David Howard. Most of you know him as an exceptional head...AUDIOLOGY - In conversation with Yury Konstantinovich Yanov
Focussing on trauma and the military, it is fitting to include this interview with ENT Professor and Russian Army General Yury Konstantinovich Yanov. Professor Gerard O’Donoghue had the honour of putting some questions to this eminent figure in Russian ENT,...
Total Otolaryngology - Head and Neck Surgery
This single volume, 1098 page book with 667 illustrations, covers all aspects of otolaryngology in both theory and practice. Compiled together by a team of world renowned co-editors from North America, as well as authors from differing specialities, this book...Audiology and ophthalmology: a comparative perspective on diagnostics and patient care
What are the similarities and differences between audiology and ophthalmic practices, and what can we learn from each other? Rosalyn Painter finds out. I’m here with Chris Gordon and Anthony Vukic from Gloucestershire Hospitals NHS Foundation Trust to find out...Current considerations on neural development and hearing loss in young children
The young child’s brain has the ability to change in response to new stimuli, resulting in learning, the foundation of adaptive and intelligent behaviour. For children with hearing loss, a reduction or lack of auditory stimuli can have a ‘lifelong...
