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2477 results found

Airway intervention for epiglottitis

This Japanese study was a retrospective review of 83 patients admitted with epiglottitis over a 9.5-year period. The authors found that the factors that were significantly more likely to be present in patients who received airway intervention were: odynophagia; drooling;...

Another use for Tisseel – plugging of the round window

After insertion of a cochlear implant electrode through the round window, there are several methods of sealing the perilymph leak and in my experience fascia (with varying amounts of attached muscle) seems to be most commonly used. Stephen O’Leary’s group...

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

A drug to prevent hearing loss caused by ototoxic therapeutics

This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...

Role of ultrasonography-guided fine-needle aspiration in management of the neck after chemoradiotherapy

Primary chemoradiotherapy (CRT) is a well-established treatment for locally advanced head and neck squamous cell carcinoma (HNSCC). However, not every patient has a complete response to this treatment modality, necessitating eventual salvage neck dissection. Some patients with persistent adenopathy following...

Invasive differentiated thyroid cancer

The majority of patients presenting with differentiated thyroid cancer have early small disease with excellent long-term outcomes. However, aerodigestive tract invasion is reported in around 10% of case series and is a poor prognostic factor. This article has been authored...

Swallow assessment: is clinical judgement or objective measurement more reliable?

Swallowing difficulties are life threatening and are the most common referral reason to speech and language therapists working with the adult population. Video fluoroscopic examination is a common instrumental tool used to assist in the assessment of the risk of...

Deep space neck infections and their management

This article explores the approach to managing patients with deep space neck infections. Clearly, an understanding of the fascial planes within the neck is required which then provides an understanding of the route of spread in these cases. The authors...

Carotid paragangliomas and their management

Paragangliomas in the head and neck are most frequently associated with the carotid artery, classically at its bifurcation and splaying the internal and external vessels. Despite their commonality at this site, large studies of these rare tumours are still lacking...

The initial management of nasal trauma

Fractures of the nose are the most common facial fractures and reported to be the third most common fracture of the human skeleton. Nasal trauma can lead to obvious or more subtle loss of function or form and cosmetic compromise....

Vestibular screening in occupational medicine

Occupational vestibular disorders carry a high medico legal and economic burden. The occupational medicine physician must rely on rapid, non-invasive, economical and reproducible screening tests. This article compares the simplified caloric test of Veits (CTV) with the skull vibration-induced nystagmus...

The effect on taste buds due to severing of the chorda tympani nerve

The long-term histological effect on taste buds following cutting of the chorda tympani in humans is not clear. Confocal laser scanning allows in-vivo examination of the same group of taste buds and is aiding our understanding of why patients recover...