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Previous radiotherapy does not cause worse outcomes in patients with differentiated thyroid cancer
Radiation exposure from nuclear incidents, especially in childhood, is known to increase the risk of thyroid cancer. This large retrospective study from the Memorial Sloan Kettering Cancer Centre sought to determine if thyroid cancers in patients with prior exposure to...
eNOS and OME
The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...
An overview of cranioplasty
This article provides a summary of the indications, materials and current techniques available in cranioplasty. Cranioplasty is performed to restore the normal architecture of the skull following craniectomy for many reasons including intracranial infection, trauma and neoplasm. The timing of...
Paper patching for aural fullness
This Belgian prospective study reported on the effect of paper patching on aural fullness of unknown aetiology. It looked at 22 patients who complained of aural fullness without any middle ear pathology. The patients were divided into a treatment group...
The effect of adenotonsillectomy on the immune system
Parents often ask about the effect of adenotonsillectomy on the immune system, with concerns that the child may be prone to more infections postoperatively due to the absence of immune tissue. This Belgian literature review looked at the local and...
Relationship between early language delays and long-term outcomes
This epidemiological study from Australia, spanning 16 years, explores the influence of early language delays over time on outcomes in affected adults. Based on vocabulary skills at age five, the study population was classified into four groups: persistently good, persistently...
Awareness of alternative techniques in cochlear implantation
The use of alternative techniques for cochlear implantation is indicated in unusual cases where the standard procedure would not be suitable. The authors of this study highlight the various reasons as to why an alternative technique might be sought, and...
Management of the ear in cleft lip and palate
The management of patients with cleft lip and palate includes a focus on effective speech and language function. Poor eustachian tube function and middle ear dysfunction mean over 90% of children suffer from otitis media with effusion. This article provides...
Swallow assessment: is clinical judgement or objective measurement more reliable?
Swallowing difficulties are life threatening and are the most common referral reason to speech and language therapists working with the adult population. Video fluoroscopic examination is a common instrumental tool used to assist in the assessment of the risk of...
What should be considered a ‘close’ margin in oral cavity squamous cell carcinoma?
Achieving clear margins during surgical resection in oral cavity squamous cell carcinoma (OCSCC) is thought to reduce local recurrence (LR) and improve prognosis; however, what constitutes a clear, close, or involved margin is inconsistent in the literature and in practice....
Stimulation for a good night’s sleep
This article was an interesting read. It is an update from the authors’ original paper printed in the NEJM in 2014 regarding the results of an implantable pulse generator (IPG) for stimulating the hypoglossal nerve in response to respiration. This...
