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1147 results found

The association between pregnancy and otosclerosis could be due to psychosocial factors around parenthood rather than biological factors

The association between pregnancy and otosclerosis is controversial. If pregnancy physiologically increases the likelihood of otosclerosis progression, then one would expect that there would be a difference between male and female patients with regards to whether having children affects how...

Is it beneficial for children to undergo bilateral cochlear implantation before 12 months old?

Universal newborn hearing screening has allowed early diagnosis and, subsequently, early intervention in hearing loss. In 2020 the Food and Drug Administration candidacy criteria for cochlear implants (CI) expanded to include profound sensorineural hearing loss (HL) in children as young...

Leisure listening does not affect the hearing of young people

The existing literature highlights concerns regarding the possibility of leisure activities involving listening to music on portable music players causing hearing loss. However, there is much speculation regarding actual effect. This article outlines a project involving young persons aged between...

Paediatric hearing following chemotherapy

This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...

How young is too young for tympanoplasty?

This paper presents the largest series of pre-school age children undergoing tympanoplasty compared with older children. The authors have collected much prospective data on 259 children undergoing 284 surgeries so were able to perform multivariate analysis. The age groupings of...

Omalizumab for CRSwNP: a monoclonal antibody

A prospective study from London, evaluating the response of chronic rhinosinusitis patients with nasal polyposis who were being treated with monoclonal antibody against IgE for severe allergic asthma. Thirteen patients were treated with Omalizumab, according to UK guidelines for their...

CRSwNP, another monoclonal antibody

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...

Where is it?

Humans’ ability to process sound is a multi-faceted phenomenon. It is a marvel which likely changes through our ageing process and is influenced by a myriad of factors. This paper examines the particulars of the dimensions of sound processing –...

Implantation Otology & Inner Ear Therapeutics Issue I

To skip directly to features, click the links below: Welcome from the editor - by Prof Manohar Bance Industry News Genomic therapies for hearing loss - by Manohar Bance Cell-based therapies - by Jennifer Harre, Athanasia Warnecke, Hinrish Staecker, Eva...

Take a breath between mouthfuls

Pulse oximetry provides a measure of the percentage of oxygen in the blood. The usual range of readings on pulse oximetry is 97-99%. Older people may have lower pulse oximetry readings than younger people, and young women have higher readings...

A trial of house dust mite sublingual tablet in children with allergic rhinitis

The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...

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