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Central auditory changes in SNHL
Robert Harrison discusses some of the most obvious ways in which cochlear hearing loss has central consequences. It is convenient to classify hearing loss according to the most obvious site of lesion, for example, conductive, cochlear, retro-cochlear, or central hearing...
Medical control of allergic rhinitis in children
The authors of this randomised trial aim to answer an important question – which is better: daily versus on demand use of intranasal steroids (fluticasone probionate) or antihistamines (levocetirizine dihydrochloride) for symptomatic control of allergic rhinoconjunctivitis secondary to pollen? The...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
COVID-19 in patients with chronic rhinosinusitis with polyps. Are they at risk?
COVID-19 entry factors are highly present in nasal epithelial cells. These factors include ACE2 and TMPRSS2. Their presence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) was not investigated before. Authors investigated expression of ACE2 and TMPRSS2 in two...The PMFA Journal - April/May 2019 issue available
FEATURES IN THIS ISSUE: An update on BIA-ALCL by Shadi Ghali / The importance of teamwork and leadership in the management of patients in burns centres by Emily Claire Taylor, Steven LA Jeffery / Focus: Opinions on regulation by Dalvi Humzah, Paul Charlson, Andrew Rankin / CPD certified: Hand rejuvenation with injectable fillers by Medhat Abdelmalek AND MUCH MORE...
Allergy testing in children with beta-lactam hypersensitivity
The beta-lactam antibiotic is commonly used in treating ENT infections in childhood. However, its use can be limited by reported hypersensitivity or allergy to the antibiotic. This is largely attributed to the previous development of skin rashes while being on...New Interacoustics VRA Screen
Interacoustics is proud to introduce VRA Screen, a visual reinforcement audiometry (VRA) solution for pediatric audiometry.
Difficult consultations with HPV-positive oropharnyeal cancer patients
The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...In conversation with Professor Paul J Donald
Prof Paul J Donald has recently stepped down as Chairman of the ORL-HN Department at UC Davis in Sacramento and is winding down to retirement. In this interview with Prof Pat Bradley, Prof Donald explains some of the highlights of...
The polyp shrinker
Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...
