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The polyp shrinker
Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...
Quality of life in children following balloon Eustachian tuboplasty
This study aimed to demonstrate the efficacy of balloon Eustachian tuboplasty (BET) in children by assessing their quality of life with the Otitis Media-6 questionnaire (OM-6). The OM-6 questionnaire is the most frequently used instrument to measure health-related quality of...
Compress to suppress the venous tinnitus
This interesting retrospective case series analyses the effectiveness of a modified surgical technique with retromastoid reconstruction of the sigmoid sinus by mechanical compression with Surgicel and bone wax packing under local anaesthesia for patients with venous pulsatile tinnitus related to...
The use of repositioning chairs in the diagnosis and treatment of BPPV
The authors performed a systematic review assessing the utilisation of multi-axial repositioning chairs, such as the TRV chair and the Epley Omniax Rotator, in the diagnosis and treatment of BPPV. They reviewed nine studies, of which four were prospective studies....
Immunosuppresants and ototoxicity
There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...
Relationship between high resolution radiological features of the otic capsuleand audiometric parameters in patients with otscerosis
The audiometric pattern in patients with otosclerosis and outcomes of stapedectomy are variable. Whether this has anything to do with the number of sites affected by otosclerosis in the otic capsule and the disease pattern according to foci location, foci...
How to improve olfaction and enhance quality of life after laryngectomy
Total laryngectomy diverts airflow away from the nose and, hence, olfaction is greatly impaired. Undoubtedly, this affects quality of life in terms of loss of taste and flavour. Surgery and devices to re-establish airflow into the nose can be difficult...
Bones, stones and surgical moans: rethinking PTH dynamics in parathyroid surgery
Intraoperative parathyroid hormone (IOPTH) testing has revolutionised minimally invasive unilateral parathyroidectomy (MIP) as the gold standard treatment for primary hyperparathyroidism, replacing old-timey four-gland exploration. IOPTH testing ensures reliable excision of all hypersecreting glands, including those pesky hard-to-find ones, without relying...Alternative listening devices: reaching the places hearing aids don’t
The stigma surrounding hearing aids means that many people who would benefit from wearing them are put off from doing so. Alternative listening devices could provide the solution to this. David Maidment discusses these devices, their effectiveness and the impact...High praise for Peptest®: diagnosing LPR with confidence
BIOHIT HealthCare recently filmed an exciting testimonial video with Jane Shaw, Consultant Speech and Language Therapist (SLT) at Doncaster and Bassetlaw Hospitals NHS Trust.Supporting the definitive diagnosis of LPR
Voice disorders affect one in 25 people in the UK, and laryngopharyngeal reflux (LPR) is a common culprit. LPR occurs when the stomach contents – including strong digestive enzymes like pepsin – flow back up into the throat, causing inflammation...
