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Expanding the role of FNA in thyroid nodule decision-making
Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...
A mouth-rinse test that can screen for oral cancer?
This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...
Family-centred early hearing detection and intervention
This mixed-methods study provides important insight into how caregivers in South Africa experience early hearing detection and intervention (EHDI) services. Using both survey data and narrative interviews, the authors explore how well current services reflect the principles of family-centred early...What’s new in auditory processing?
Auditory processing disorder (APD) has had a controversial history, stemming mainly from lack of scientific rigor and accepted clinical definition. That situation is now changing. Driven by the huge number of people with unaddressed listening difficulties, basic discoveries in neuroscience,...
Is major ear surgery financially viable?
It is difficult to ignore the present reality in the NHS that understanding clinical coding is perhaps of more relevance to the practising clinician than the human genome! Clinician engagement is becoming more essential to protect patient care and maximise...
How effective are our two-week-wait guidelines in picking up head and neck cancer?
With a 30% increase in the incidence of head and neck cancer since 1999 in the UK, it is important that the two-week wait referral guidelines safely encompass all risk factors but also render these urgent referrals based on signs...
How do mermaids hear?
When the imagery of childhood fairy tales meets the more clinically analytical mind of an adult, there may at some point come the question, ‘how do mermaids hear’? Luckily a department of biology in Denmark has sought to furnish such...
