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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody

Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...

Olfactory and gustatory recovery in coronavirus patients after six months

It remains unclear for how long olfactory and gustatory losses persevere in patients with COVID-19. This is a prospective study of 300 patients who lost taste and smell within seven days of contracting COVID-19. The patients were objectively assessed with...

A new treatment for chronic rhinitis

The review paper looks at the efficacy of cryoablation of the posterior nasal nerve (PNN) to treat chronic rhinitis, an increasingly popular method of treating a highly prevalent and morbidity-inducing disease. Five studies were included in the meta-analysis, all dating...

Long-term results for dupilumab are very promising!

Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...

A useful adjuvant treatment for SNAC or IP

5-Fluorouracil (5FU) is a topical preparation used in the treatment of various dermatological, ocular and gynaecologic malignant and pre-malignant conditions, and this literature review looks at the efficacy of 5FU in treating inverted papilloma and sinonasal tumours. The authors cite...

A ‘Clear Way’ Forward in Foreign Object Removal – Sterile Single-use Clearway Suction Handle

DTR Medical’s UK manufactured Clearway Suction Handle is the instrument of choice for foreign body removal.

Setting up a robotic surgical practice: view from India

Transoral robotic surgery has an established role in head and neck cancer surgery. But how easy is it to set up a service in a resource-constrained environment? Gouri Pantvaidya and Ameya Pai give us a view from the Indian subcontinent....

Developmental stuttering: a speech-motor impairment with sensory aspects

In treating patients who stutter, understanding the effects of sensory input (i.e. auditory input) can help to direct therapeutic approaches. Sensory processing has been identified as a contributory factor in several diagnoses, notably autism and ADHD [1], however it has...

The history of bone-conduction devices

The evolution of bone-conduction hearing devices from the 1400s’ rudimentary designs to today’s advanced models has greatly improved hearing for individuals with conductive or mixed hearing loss. This article delves into the history and technical advancements over the years, as...

In conversation with Dr Narveshwar Sinha

‘Only if you hear, you speak’ – early diagnosis of deafness On the occasion of World Hearing Day, Vikas Malik interviewed Narveshwar Sinha, Chairman of IDEAL Charity, a UK-based charity working for the hearing impaired in less developed countries for...

Reflections on virtual teaching

In a situation where we cannot meet our students (whether they be medical professionals or non-medical), how do we maintain their education? Peter Samuel has been speaking to some colleagues on how they have risen to the challenge. The COVID-19...