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Hydrogen peroxide and its uses in healthcare

This is an interesting review about the origin and uses of hydrogen peroxide, especially in neurosurgery. However, its uses are ubiquitous and applicable to several medical specialties. When hydrogen peroxide was first discovered in 1818 by Louis Thenard, it had...

Inpatient or outpatient thyroidectomy?

This systematic review and meta-analysis discusses the safety of hemithyroidectomy in an outpatient vis-à-vis an inpatient setting. Thyroidectomy has traditionally been performed as an inpatient procedure. Currently, an increasing number of surgeons are performing thyroidectomy in outpatient settings. The main...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Rosemary oil to aid surgical healing?

There are a multitude of ways in which to damage the nasal epithelium, whether iatrogenically through nasal surgery, via injury, allergy, infection or inhalation of an environmental pollutant. This study looks at the role of the herb rosemary, in the...

Idiopathic sudden sensorineural hearing loss and vertigo

This prospective longitudinal study evaluated vestibular function inpatients with idiopathic sudden sensorineural hearing loss (ISSHL) using caloric and video head impulse tests. All patients were admitted for treatment of their ISSHL and divided into two cohorts depending on presence or...

Posterior nasal neurectomy – long-term data shows tailing off of benefits but still improvement after three years

It is well understood that allergic rhinitis has a very detrimental effect on quality of life for afflicted patients. This study looks at patients with allergic rhinitis but no other associated sinonasal or respiratory diagnoses. Patients with a history of...

Temporal bone fractures in children – are we doing enough?

This is a retrospective study which assessed clinical presentation and prognosis in 91 children under the age of 18 who developed temporal bone fractures from trauma, the commonest of which was falls from heights followed by motor vehicle accident. The...

Human immunodeficiency virus and hearing impairment

With an estimated 36.7 million individuals living with HIV / AIDS and literature reporting that these conditions contribute to hearing loss, it is surprising that more focus and resources are not employed to tackle this major hearing health concern. Yolandé...

Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

Getting to grips with acoustic trauma

Our understanding of hearing loss caused by noise exposure to those in the armed forces is growing in interest and understanding. Research at a cellular level is essential to increase our understanding so that we can better diagnose, manage and...

Recalcitrant chronic rhinosinusitis: What to do next?

Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...

Can we prevent chronic rhinosinusitis?

The old adage ‘prevention is better than cure’ is considered by Professor Hopkins in respect to chronic rhinosinusitis, a condition affecting around 10% of the adult population and associated with huge impact on quality of life and economic cost. A...