You searched for "tympanic"
OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...
Laser for active mucosal chronic otitis media
Active mucosal chronic otitis media (COM) is a condition characterised by otorrhoea secondary to chronic inflammation of the middle ear and mastoid mucosa associated with granulations and a tympanic membrane perforation. Surgical intervention is often required, but concurrent mastoidectomy with...
Does stress and anxiety worsen idiopathic sudden hearing loss outcomes?
There have been suggestions that the natural course of the idiopathic sudden sensorineural hearing loss (ISSNHL) is not affected by intensive therapy. There is speculation as to whether unknown factors affect the treatment prognosis. This is a retrospective study of...
Mastoid obliteration for canal wall down surgery
Surgery for acquired cholesteatoma is varied amongst surgeons with some only performing combined approach tympanoplasty. The change in lifestyle for patients with canal wall down surgery is significant and hence this group in Japan looked at 118 adult patients with...
Valsalva manoeuvre treatment of otitis media with effusion in adults
Otitis media with effusion (OME) is common in children but has a low prevalence in adults. There is some evidence to advocate middle ear inflation as a successful treatment for children with OME. This form of treatment is also recommended...
Office-based otology procedures
This edition of the Otolaryngologic Clinics of North America covers office-based surgery in ENT. This article discusses procedures in otology that could be performed in the outpatient setting and covers innovations in office-based otologic procedures. The endoscope features prominently in...
Stapedotomy in osteogenesis imperfecta
Osteogenesis imperfecta (OI) is a rare connective tissue disease caused by a defect in collagen structure. Hearing loss is a characteristic feature of OI. It typically presents with conductive hearing loss initially, followed by a superimposed sensorineural component later in...
Surgical outcomes of myringoplasty using platelet-rich plasma
Tympanic membrane (TM) perforations can affect people’s quality of life due to recurrent infections. Management is often by surgical repair. In this study, the authors investigated the outcomes of a minimally invasive approach of patch myringoplasty using an atelocollagen sponge...
A novel graft material for endoscopic tympanoplasty using the pre-tragal SMAS layer
The traditional biological graft materials for providing a scaffold for tympanic membrane reconstruction include temporalis fascia as well as conchal and tragal perichondrium/cartilage. This group from Taiwan present a novel graft option using the superficial musculo-aponeurotic system (SMAS) layer. They...
Non-autologous graft material in paediatric tympanoplasty – is it as good as temporalis fascia and is it cost-effective?
This retrospective case review looks at the experience of a single unit using a variety of autologous (temporalis fascia, n=292) and non-autologous graft material, n=241 (alloderm (human dermis), biodesign (porcine submucosa, $170-$255) and tutoplast (human pericardium, $350). The average patient...
