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The microbiological environment of the paranasal sinuses

This article reviews the ecology of the sinuses and tries to make sense of the confusing literature on the subject. This covers the details of molecular studies, particularly those which attempt to differentiate normal sinuses from those in patients with...

Those little friends in our noses

Human microbiota plays an important role in both health and disease including metabolism, immunomodulation, and a potential role in chronic inflammatory conditions such as chronic rhinosinusitis (CRS). The authors aimed to investigate the sinonasal microbiome using 16S rRNA gene sequencing...

Update on orbital complication of acute sinusitus

This study aims to illustrate the Graz experience. The study is retrospective, 53 patients with orbital complication of sinusitis were examined / confirmed by a University Hospital from 2000 to 2011. Thirty-seven underwent surgery, seven of which experienced a recurrence....

What is in the Fountain of Youth?

Does the auditory system have to age? Can we become more like turtles or jellyfish and keep our internals running without degradation? This essay considers the theoretical underpinnings of biological processes in the cochlear, in particular the role of the...

The evidence for various treatments of autoimmune ear disease

The difficulty with this disease entity is that it is a heterogeneous group of conditions affecting the ear and a widely accepted diagnostic criteria does not exist. It is therefore difficult to conduct a well controlled trial and this systematic...

Simple preoperative tests predicting outcomes for ESS patients?

We are all familiar with patients suffering extensive nasal polyps who relapse all to soon after careful and thorough endoscopic sinus surgery (ESS). This paper looks to answer whether we can predict which patients will do well, and which less...

Microsurgical Management of Middle Ear and Petrous Bone Cholesteatoma

Several years ago, after being appointed as a consultant, my esteemed senior colleague entered my office and questioned why I was reading a textbook at that stage of my career, suggesting that I should be focusing solely on journals. Whilst...

Can smaller cancer centres deliver high quality care for patients with laryngeal cancer?

There is a continuing conflict between treating patients as close to their homes as possible and centralising specialised services, taking into consideration the critical mass and the multi-disciplinary expertise available. This is a report of outcomes in the treatment of...

The continued evolution of surgical techniques for bone anchored hearing devices

This paper is not the first, and is unlikely to be the last, to look at a variation on the current technique for inserting the percutaneous titanium bone-anchored component of a bone conduction hearing device. In less than a decade,...