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417 results found

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Describing the most useful OSA assessment?

This article sets out to comprehensibly describe drug induced sleep endoscopy and its role in determining the level of obstruction in patients with OSA. The advantages described include the fact that other techniques, including Muller’s manoeuvre, have significant variation in...

Surgically improving pharyngeal paralysis and associated dysphagia

This was an interesting article explaining the current methods used to try and improve dysphagia and in some cases associated problematic aspiration following vagal injury. These patients are often those with other associated cranial neuropathies, with skull base lesions, brain...

Invasive differentiated thyroid cancer

The majority of patients presenting with differentiated thyroid cancer have early small disease with excellent long-term outcomes. However, aerodigestive tract invasion is reported in around 10% of case series and is a poor prognostic factor. This article has been authored...

Association of childhood OME with obesity

Many factors influence the development of otitis media with effusion (OME) in children, some of them being increased plasminogen factor inhibitor (PAI-1) levels, eustachian tube obstruction and gastro-oesophageal reflux. These factors are also associated with obesity. Sixty children with mean...

Deep space neck infections and their management

This article explores the approach to managing patients with deep space neck infections. Clearly, an understanding of the fascial planes within the neck is required which then provides an understanding of the route of spread in these cases. The authors...

Chronic rhinosinusitis and sleep

This is an interesting article from the Chung Shan Medical University in Taiwan. One-hundred-and-thirty-nine patients were enrolled into this five-year study. They all had chronic rhinosinusitis with or without polyposis and underwent sinus surgery. The aim was to investigate a...

Maternal angst

This paper confirms the anxiety that a mother experiences when their child undergoes surgery. The paper focuses on adenoidectomy and adenotonsillectomy for moderate to severe upper airway obstruction showing admirably how anxiety reduces following surgery. The authors recruited 66 mothers...

Surgical and non-interventional management of laryngomalacia

In this elaborate review article, the authors have described various aspects of laryngomalacia and its surgical management with supraglottoplasty or otherwise, gleaned from an extensive review of the literature which provided evidence or the lack of it in relation to...

Pyriform turbinoplasty

This article describes a new operative technique to improve nasal airflow, the pyriform turbinoplasty. This specifically addresses the lateral part of the nasal valve where there may be impingement into the airway in select patients. This corresponds to the area...

Radiofrequency for tonsillectomy

This Turkish study compared the use of radiofrequency (RF) tonsillectomy to the more traditional cold steel dissection (CD) technique. The authors enrolled 114 patients undergoing tonsillectomy for chronic tonsillitis and tonsil hypertrophy (causing upper airway obstruction) over a 4-month period....

The Impact of sleep endoscopy for paediatric obstructive sleep-disordered breathing

Paediatric obstructive sleep apnoea (OSA) is not always resolved or improved with adenotonsillectomy. Persistent or complex cases of paediatric OSA may be due to sites of obstruction in the airway other than the tonsils and adenoids. Investigation of paediatric obstructive...