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Developing medical devices for children: opportunities and challenges

The development of medical devices for infants and children lags significantly behind the development of devices for adults. While in the United States the Food and Drug Administration (FDA) has set up incentives for developing child age-specific pharmaceuticals, there is...

Discovery in the genetics of complex disease: Otitis media

Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...

NHS collaboration and partnership with the pharmaceutical and medical devices industries

Historically the relationship between industry and the NHS has been a cautious one. Both sides have typically worked with only partially disclosed agendas, under a pervading fear of finding themselves on the wrong end of a win-lose negotiation. Things have...

Surgical management of sleep disordered breathing

Snoring and sleep-disordered breathing are often described as multi-level problems, and different surgical procedures are required to treat the various sites of airway narrowing and/or collapse. Jonathan Hobson gives us an eloquent run-through the various options available to the ENT...

Sleep apnoea in children with craniofacial syndromes

Whilst snoring and obstructive sleep apnoea are relatively common diagnoses in paediatric ENT, children with craniofacial syndromes take the problem to the next level. Robert Nash and Michelle Wyatt describe the Great Ormond Street multidisciplinary approach to treating this complex...

Robotic head and neck surgery: current state of the art and future innovations

Technology and innovation has provided modern head and neck surgeons with successive generations of robotic surgical systems, fibre-optic lasers, and novel tools which have ushered in a new era of minimally invasive surgery for tumours of the pharynx and larynx....

Adolescence, drug use and body image

Teenagers are notoriously conscious of how they are perceived by others. Dr Saraiva and colleagues explain how this can lead to problems with substance abuse for both boys and girls, and discuss the different substances they may encounter. Adolescence is...

Addressing ear and hearing care through task sharing: the Malawian experience

How can ear and hearing care be addressed in a setting with limited resources? Wakisa Mulwafu, Chris Prescott and Johan Fagan present an innovative model for training ear surgery technicians to perform endoscopic myringoplasty under local anaesthesia on a large...

Sniffing out the evidence – COVID-19 and loss of sense of smell and taste

Louis Pasteur once observed: “In the fields of observation chance favors only the prepared mind.” Professor Hopkins was certainly prepared when a few anecdotes of smell problems started to accumulate early in the pandemic’s course. Post-viral olfactory loss is nothing...

Robotic surgery for squamous cell cancer: the new frontiers

Although the da Vinci platform was FDA approved for early-stage oropharyngeal cancers, the indications have expanded. In this article, John Hardman explains how surgeons, with greater understanding of the strengths and limitations of robotic surgery, have systematically set out to...

In conversation with John Carlisle: the silent hero shaping medical publication integrity

Have you ever been curious as to what your anaesthetist is getting up to on their laptop during long cases? Me neither, but I always generally assumed they were trading Bitcoin, solving the Riemann hypothesis and buffing their Tinder profile....

Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...