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CRSwNP, another monoclonal antibody
Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...
Validating a new international cholesteatoma classification – a necessary but challenging task
A European and Japanese joint consensus statement was published in 2017 which proposed a new cholesteatoma staging classification (EJS), with four stages. This follow-up publication aims to assess the internal and external validity of the staging system using existing prospectively...
Cocaine detection hours after FESS
This is a very interesting article from Australia regarding the bioavailability of cocaine following atomised application prior to endoscopic sinus surgery. The well-established practice of preparing the nasal mucosa for sinus surgery involves the placement of a usually modified Moffett’s...
Vocal fold motion impairment following intubation – how likely is it to recover?
Ed’s Choice reviews a timely paper investigating prolonged intubation on vocal fold motion. The current scientific literature is dominated by studies examining COVID-19 and its widespread effects on health and healthcare delivery but will be old news by the time...
Lockdown has been bad for children, but it might mean they don’t need surgery anymore
Our editor’s choice for this edition reviews an article looking at the effects of lockdown on symptom prevalence in children with adenotonsillar diseases. In this unprecedented COVID-19 era that we are all living and working in, risk assessment has taken...
The basis of auditory processing disorder: what can we learn from corticals?
Auditory processing disorder (APD) is a poorly understood, heterogenous and surprisingly common condition. It manifests as a perceptual difficulty in centrally processing auditory information. Diagnosis is usually based on a variety of behavioural tests involving verbal and non-verbal assessments. In...
Complications associated with intra-tympanic steroid injections for sudden sensorineural hearing loss
Around 15,000 people in the UK experience a sudden sensorineural hearing loss (SSNHL) each year, and in the majority of cases the cause is unknown. Treatment options for idiopathic SSNHL include various modalities of steroid treatments which have known limitations...
Cognitive function is preserved in episodic vestibular disorders
Cognitive deficit in bilateral vestibular failure in particular, but also in unilateral vestibular failure, is well documented. The authors designed this prospective study to determine if deficits in cognition, as well as anxiety and depression, were present in episodic vestibular...
Persistent postural-perceptual dizziness (PPPD), psychosomatic or not? The debate continues
PPPD continues to provoke debate since the diagnostic criteria emerged in 2017. This review covers two commentaries because they are best considered together: the first one, by HK and BS-U, concluded that PPPD is a psychosomatic disorder (in fact, ‘a...
