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To montelukast or not to montelukast
Both histamine and cysteinyl leukotrienes play an important role in both seasonal allergic rhinoconjunctivitis (SARC) and asthma. A combination therapy against both was shown to give benefit both in vitro and in vivo. Authors wanted to test the efficacy of...
Quality of life in children following balloon Eustachian tuboplasty
This study aimed to demonstrate the efficacy of balloon Eustachian tuboplasty (BET) in children by assessing their quality of life with the Otitis Media-6 questionnaire (OM-6). The OM-6 questionnaire is the most frequently used instrument to measure health-related quality of...
Neuromodulation in drug resistant epilepsy
Treatment of epilepsy can be considered generally as medical or surgical. Anti-epileptic drugs achieve a five-year seizure freedom in 54-70% patients. It is estimated that 50-90% of patients with drug-refractory epilepsy may not be candidates for resective surgery. For example,...
Gastrostomy tube dependence following TORS
Transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma (OPSCC) is now a well-established treatment modality for early (T1-T2) disease. Accumulating evidence suggests that one of its main benefits relative to conventional chemoradiotherapy is superior long-term functional outcome, especially with...
Treatment options for vestibular neuritis: systematic review and meta-analysis
Vestibular neuritis (VN) is the third most common cause of peripheral vertigo. VN has been postulated to have viral aetiology and historically it was treated with steroids, until 2011 when a Cochrane review demonstrated lack of robust evidence behind this...
Transmastoid facial nerve decompression for persistent traumatic facial nerve paralysis
Facial nerve paralysis (FNP) can occur following trauma, with a small number of these patients requiring facial nerve decompression (FND) to aid recovery. The authors shared their experience in decompressing the facial nerve for persistent severe FNP via a transmastoid...
Unravelling the Meniere’s vs. migraine conundrum – what does the mastoid contribute?
This is an interesting observational study that attempts to classify subtypes of Meniere’s disease (MD) in relation to the coexistence of migraine. It is well known that the two conditions share common characteristics, making diagnosis and treatment challenging at times....
How long after head and neck cancer diagnosis do patients need opioids?
With the advances in the management of head and neck cancer (HNC), patients tend to survive longer after their diagnosis. These people face the burden of chronic pain management which is strongly associated with HNC. A HNC team in Portland...
A time-saving method for faster cancer diagnosis and treatment
One of the main impediments in achieving UK Government cancer diagnosis and treatment targets is lack of diagnostic capacity. An increase in head and neck cancers by 50% in the last five years has put on additional strain. In this...
Is Gamma Knife Surgery effective for intracanalicular vestibular schwannomas?
Vestibular schwannomas (VSs) are rare, occurring in approximately five per 100,000 adults a year. In circa 8% of cases, the VS is contained within the internal auditory canal, i.e. intracanalicular (iVS). Although radiosurgery is a recognised treatment modality for VSs,...
Analysing videofluroscopy: does it matter how it’s done?
Videofluoroscopy, as a tool that assesses the process of swallowing, has transformed our understanding of dysphagia. Clinicians can observe the biomechanics of a bolus moving from the oral cavity through the pharynx and oesophagus and into the stomach. Over the...
