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Sharing audio data for the greater good of research

HomeBank is a novel online repository for daylong audio recordings of children and families. Daylong recordings of children in naturalistic environments with their family and friends are an important source of information to enable an understanding of how children develop...

Invasive differentiated thyroid cancer

The majority of patients presenting with differentiated thyroid cancer have early small disease with excellent long-term outcomes. However, aerodigestive tract invasion is reported in around 10% of case series and is a poor prognostic factor. This article has been authored...

Can obstructive snoring affect the snorer’s ears as well?

Patients with obstructive sleep apnoea (OSA) often show severe nasal obstruction, chronic sinusitis and/or a deficit of nasal mucociliary clearance with nasopharyngeal stagnation of secretions possibly predisposing to eustachian tube dysfunction (ETD). This clinical prospective study investigates ETD, nasal resistance...

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...

Systematic review comparing transoral laser surgery versus open partial laryngeal surgery for advanced laryngeal cancer

The aim of this Italian systematic review was to establish outcomes (local control and survival) of conservative laryngeal surgery for advanced T stage laryngeal cancers. Articles published from 1980 onwards, had at least 10 patients that underwent partial laryngeal surgery...

Lack of early vocabulary growth in bilateral cochlear implant children

Studies indicate that children with unilateral implantation may have delayed vocabulary development for long periods of time even after implantation. This Finnish study attempted to find out whether bilateral cochlear implantation was associated with earlier vocabulary development. The authors analysed...

Blindness after orthognathic surgery

This is a case report and review of the literature of this rare, but well recognised alarming complication. The authors discuss the possible mechanisms, suggesting that it does not arise from a direct injury to the optic nerve and is...

Swallow assessment: is clinical judgement or objective measurement more reliable?

Swallowing difficulties are life threatening and are the most common referral reason to speech and language therapists working with the adult population. Video fluoroscopic examination is a common instrumental tool used to assist in the assessment of the risk of...

What should be considered a ‘close’ margin in oral cavity squamous cell carcinoma?

Achieving clear margins during surgical resection in oral cavity squamous cell carcinoma (OCSCC) is thought to reduce local recurrence (LR) and improve prognosis; however, what constitutes a clear, close, or involved margin is inconsistent in the literature and in practice....

Association of childhood OME with obesity

Many factors influence the development of otitis media with effusion (OME) in children, some of them being increased plasminogen factor inhibitor (PAI-1) levels, eustachian tube obstruction and gastro-oesophageal reflux. These factors are also associated with obesity. Sixty children with mean...

What is balloon eustachian tuboplasty (BET)?

Eustachian tube dysfunction (ETD) is the result of a combination of factors that interfere with the mucosal functional or cartilaginous structures. Failure to open the eustachian tubes can cause aural pain, pressure in the ears, muffled hearing, crackling/popping sounds in...