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Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...
Using evidence and international consensus to guide treatment of thyroid nodules
The authors of this practical review paper highlight a growing issue within thyroid surgery, where high-quality ultrasound has increased the detection of subclinical nodules: what do we do with the patient presenting with an ‘incidental’ thyroid nodule? This has both...
Prominauris: Which surgical technique to use?
Otoplasty accounted for 3.2% of all plastic surgical interventions, and 2.6% worldwide in 2015. Patient satisfaction ranges above 95% for prominent ear correction despite the myriad of available techniques in the literature associated with highly variable outcomes. The authors split...
Importance of the time interval between surgery and postoperative radiation therapy in head and neck cancer
The ideal time to start postoperative radiation therapy (PORT) in head and neck cancer patients has been an issue of debate. In the USA, the National Comprehensive Cancer Network (NCCN) recommends initiating radiotherapy within six weeks from surgery. The six-week...
KTP laser ablation for early glottic cancer
TLM for glottic carcinoma has historically been performed with a carbon dioxide (CO2) laser. A much smaller literature base has examined the use of potassium titanyl phosphate (KTP) laser in this context. This retrospective chart review aims to fill that...
Empty Nose Syndrome: Evidence Based Proposals for Inferior Turbinate Management
To cut or not to cut, that is the question… The authors of Empty Nose Syndrome emphatically implore the reader to spare the inferior turbinate, lest they cause patients this undue misery! This book is a thought-provoking journey through the...
How well do different assessments of swallowing correlate with one another?
Swallowing (dys)function may be assessed by three key measures: 1. instrumental swallowing techniques such as the modified barium swallow (MBS) or videofluoroscopy; 2. functional measures of diet texture that patients can eat comfortably (usually rated by the clinician); and 3....
Impact of the updated cancer staging system on HPV-positive disease
The AJCC cancer staging manual was updated in 2017 (8th edition). It is used in the MDT setting for planning treatment and assessing prognosis for individual patients, and is also widely used internationally in clinical trials. Unlike previous iterations of...
Method of delivery: all topical nasal corticosteroids are not made equal
There is an increasing body of evidence that the role of surgery for chronic rhinosinusitis is to facilitate the delivery of topical medical treatment – most notably, topical corticosteroids. Two recent studies, one using flow dynamics and another one examining...
Neurological complications associated with managing degenerative cervical myelopathy
Degenerative cervical myelopathy (DCM) is a common neuropathologic status due to degenerative changes to the cervical spine. There are multiple operative techniques available, including anterior cervical discectomy and fusion, anterior cervical corpectomy, laminoplasty, laminectomy and laminectomy with fusion. C5 palsy...
Allergy and the ear
Allergic disease is commonly associated with asthma, eczema and rhinosinusitis. The authors reviewed possible associations between allergy and otologic diseases. The authors first explored the possible association between allergy with otitis media with effusion (OME) and found the majority of...
