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Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...From Hippocrates to COVID-19: sniffing out the disease
The ancient Greek physician, Hippocrates, used the ‘art of smell’ to diagnose diseases around 400BC. He also formulated miasmatic theory, which posited that disease is caused by bad smells. Bad air was strongly believed by many physicians to be the...
Laryngeal disorders associated with HIV infection
Following the introduction, and now widespread availability, of combined antiretroviral therapy, HIV has become a chronic disease with minimal or indeed no negative impact on life expectancy. As a result, there is a growing public health interest in establishing the...Screening for hearing aid fittings – an approach for primary care
Introduction The communication difficulties related to hearing loss can lead to ‘depression, social withdrawal and problems with employment and access to information sources’ [1]. Furthermore, unmanaged hearing loss is associated with dementia, a poorer quality of life, depression, anxiety and...
Hidden disabilities and cochlear implantation under 12 months of age
There has been a global shift to providing children with severe-profound deafness cochlear implants (CIs) before they are 12 months old. Early intervention is critical and one of the overriding factors in successful outcomes for children with CIs. Early implantation...Early detection pathways for congenital cytomegalovirus for infants referred from the newborn hearing screen
This article discusses requirements for an early congenital cytomegalovirus (cCMV) detection pathway to ensure children do not miss out on the opportunity for timely diagnosis and treatment. The pathways described are currently in use in England and apply to well...
BPPV duration as a predictor for therapy
Benign paroxysmal positional vertigo (BPPV) is one of the most common vestibuar disorders encountered in the neurotology clinic. The majority of cases of BPPV are due to vestibuar lithiasis in the posterior semicircular canal, but there are reports of cases...
Active surveillance for papillary thyroid cancers – what is the risk of progression?
Papillary thyroid cancers (PTCs) are generally considered to be indolent malignancies with favourable outcomes. Active surveillance (AS) has consequently been trialled as a management option for small PTCs with no evidence of regional lymph node involvement, especially papillary thyroid microcarcinomas...KUDUwave™ Boothless Audiometer
The KUDUwaveTM was designed to replace the need for a sound booth and enable truly portable audiometry in almost any environment. ENT & Audiology News’ own Gareth Smith, Priya Carling and Alex Griffiths Brown met in London to put the...
Medical information required with requests for CT scans of the temporal bones; a two cycle audit
It is a common experience that radiology reports on the CT scans of the temporal bones do not always reach a diagnosis. Various studies have produced differing results in that detailed information may not be necessary to help reach a...
