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How effective are our two-week-wait guidelines in picking up head and neck cancer?
With a 30% increase in the incidence of head and neck cancer since 1999 in the UK, it is important that the two-week wait referral guidelines safely encompass all risk factors but also render these urgent referrals based on signs...
Endoscopic transsphenoidal surgery versus dopamine agonist therapy for microprolactinomas
This study addresses the importance of the location of microprolactinomas in determining prognosis after surgery. Long-term dopamine agonist treatment is the current standard of treatment for microprolactinomas. However, patients often seek surgical removal. The authors of this study retrospectively analysed...
Chorda tympani in middle ear surgery
This was a prospective study at a single Belgian centre that aimed to monitor postoperative taste problems after middle ear surgery. The authors also looked at the influence of pathology and manipulation of chorda tympani (CT) on its function. Taste...
A cost reducing protocol for magnetic resonance imaging in patients suspected to have acoustic neuroma
Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have an acoustic neuroma. However, inappropriate referrals for imaging are not helpful, especially with the growing need to reduce costs. In this study the authors compared two audit...
Hearing outcomes after retrosigmoid resection of smaller vestibular schwannomas are better
The authors reviewed published literature reporting hearing outcomes in patients after retrosigmoid (RS) resection of vestibular schwannoma (VS). Aggregate hearing preservation of 31% and 35% under fixed and random models respectively was observed in the 2034 patients meeting eligibility criteria...
Location, location, location: How to get the steroid where you need it, in chronic rhinosinusitis
What almost all current guidelines on chronic rhinosinusitis have in common is the importance of intranasal steroid (INCS) use. However, it is increasingly understood that the efficacy of INCS depends on their efficient delivery to the point of need, i.e....
Noise tolerance in the presence of speech
Noise is a common issue reported by people in reference to speech understanding, both for normal and hearing-impaired people. This study investigated how noise loudness, annoyance, distraction and speech interference impact noise tolerance in normal hearing people while listening to...
Sinonasal inverting papilloma and HPV - a meta-analysis of recurrent tumours
Sinonasal inverting papilloma (SNIP) is a common benign tumour of the sinuses. Difficulty lies in the association with metachronous or synchronous SCC of the sinus and also in the complete removal of the lesions due to their anatomical location. An...
Polypharmacy in the vestibular clinic
Polypharmacy is defined as the simultaneous use of five or more medications and its prevalence is increasing. Dizziness or vertigo are common side effects of polypharmacy. Despite advancements in patient data management, there remains limited information on polypharmacy in patients...
Biopsy sites with a diagnosis of pemphigusand mucous membrane pemphigoid
This is a systemic review and met-analysis to critically evaluate optimal biopsy site for patients presenting with pemphigus or mucous membrane pemphigoid. Historically, diagnosis is made if H&E staining direct immunofluorescence and serological testing of auto-antibodies. Direct immunofluorescence has been...
