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Bevacizumab, NF2, hearing and age

Introduction NF2-related schwannomatosis (NF2-SWN) is an autosomal dominant disorder leading to the development of schwannomas, meningiomas and spinal cord ependymomas. Younger age is a negative prognostic factor. Treatment includes observation, surgery, radiotherapy and medical therapy with bevacizumab (VEGF monoclonal antibody)....

EVOTION: Big data supporting public health policies for hearing loss

Big Data? Biosensors, smart hearing aids and smartphones? The EVOTION Project has it all and more! What will this project tell us about the future of hearing management? Doris-Eva Bamiou, Giorgos Dritsakis and Louisa Murdin, members of the EVOTION team,...

Tinnitus in middle-age: prevalence and incidence

Population-based studies of tinnitus provide crucial underpinning evidence which highlights the need for further research on the effective diagnosis and clinical management of this heterogenous condition. Furthermore, such studies provide evidence of the burden of this condition both on the...

Better Hearing with Cochlear Implants

This soft cover book of 453 pages describes in detail the work undertaken at the Research Triangle Institute (RTI) in North Carolina which has led to many of the designs and theories of speech processing in cochlear implantation. It is...

Binaural Interference: A Guide for Audiologists

This book details what binaural interference is, it looks at the basic principles of this topic and follows the research over the years that has gone into investigating what causes binaural interference. It makes for an interesting read, covering a...

Hearing Science Fundamentals – Second Edition

The second edition of Hearing Science Fundamentals is a simply and clearly written introductory text, ideal for students beginning their training. It covers topics ranging from anatomy and physiology to auditory perception. This edition includes nine new chapters in addition...

Helicobacter pylori and chronic tonsillitis

Helicobacter pylori infection in the stomach has long been associated with chronic gastritis, duodenal and peptic ulceration and even gastric cancer. Whether laryngopharyngeal reflux (LPR) brings up these organisms and induces chronic tonsillitis is an interesting concept, which the authors...

Novel wax solvent

This paper describes an open label, prospective study undertaken by the authors to demonstrate the safety and efficacy of a novel topical wax solvent. This new product has a dual action using a bicarbonate system to disrupt the esters and...

Diagnosis of obstructive sleep apnoea hypopneoa syndrome (OSAHS) without sleep studies

Polysomnography is considered the ‘gold standard’ in the diagnosis of sleep apnoea but it is expensive and difficult to perform in children. Diagnosis based on subjective judgement is often inaccurate. An accurate diagnostic scale based on clinical parameters could obviate...

Increased intensity of treatment: intensity does not improve outcomes

There is a paucity of reports regarding the intensity and appropriate duration of treatment required to improve the language abilities of children with language impairment. This study used direct measures such as the time spent on language, the frequency, number...

Rates of tonsillitis increase as rates of tonsillectomy reduce

This retrospective study sought to determine the effect of reduced rates of tonsillectomy in England and Wales, over a 13-year period, on rate of hospital admissions for the complications of acute tonsil infection (acute tonsillitis and quinsy), and hospital bed-day...

Sublingual house dust mite immunotherapy

House dust mite immunotherapy in allergic rhinitis was shown to be effective in trials with a relatively small number of participants. The authors of this study performed a multicentre double-blind randomised controlled trial to investigate effects of house dust mite...