You searched for "biopsy"

94 results found

Occurrence of cancer in asymmetrical tonsillar enlargement in adults

With significant increase in head and neck cancer in the last decade, attributed to HPV, fast-track referrals from primary care have markedly increased, adding further to the burden on the NHS. Whether or not unilateral tonsillar enlargement alone, without red...

Modifying two-week wait protocol for suspected head and neck cancer patients during COVID-19

As healthcare workers, we are committed to ensuring that our patients continue to receive the optimum care that we are set up to deliver. However, the last year has shown that we need to be mindful of balancing this with...

Transnasal oesophagoscopy (TNO) and balloon dilatation under a local anaesthesia

Many of us are becoming more and more familiar with the use of transnasal oesophagoscopy. It has a number of well-described uses in the outpatient setting and is well tolerated by our patients. Yakubu Karagama describes taking this technique a...

Evidence for diagnostic role of narrow band imaging in the outpatient setting for head and neck squamous cell carcinoma

Narrow band imaging (NBI) uses light in the blue and green spectrum to differentiate areas of carcinoma from normal or inflammatory tissue. This tertiary referral head and neck unit in Spain used white light endoscopy as initial screening for all...

What is the evidence for contralateral tonsillectomy in TORS for known unilateral tonsil malignancy?

The concept of field changes by carcinogens within the upper aerodigestive tract is well established with reported rates of synchronous tumours of 4% and second primaries of 36%. The tonsil in particular has the highest rate of synchronous tumours, postulated...

The role of imaging in differentiating rare temporal bone neoplasms

This paper provides a useful tool to assist in determining the diagnosis of benign neoplasms of the temporal bone using readily available imaging modalities. Specifically, this group have looked at chondrosarcoma, an expansile hypermetabolic mass lesion usually found in the...

A mouth-rinse test that can screen for oral cancer?

This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...

Advances in diagnosis and management of allergic rhinitis

This article reviews advances in the diagnosis and management of allergic rhinitis. Recent advances in the diagnosis of allergic rhinitis include testing of local immunoglobulin E (IgE), urinary test to diagnose aspirin hypersensitivity and optical rhinometry to assess degree of...

Beware of GPA as a cause of subglottic stenosis

Up to 92% of patients with granulomatosis with polyangiitis (GPA) have concurrent ENT manifestations of the disease. Whilst we are familiar with sinonasal and middle ear presentations of GPA, subglottic stenosis (SGS) is another important and potentially life threatening manifestation....

Food impaction in children is associated with eosinophilic oesophagitis

There is an increasing amount of evidence to suggest that chronic oesophageal inflammation and motility disorders play a more significant role in oesophageal food impaction (EFI) in children compared to structural defects. The authors conducted a retrospective study of children...

Recurrent seroma in cochlear implanted patients

Little is known about why some patients experience recurrent seromas over the implant package and in the absence of any cause, antibiotics are frequently prescribed as a precaution to protect the implant from infection. A tertiary referral centre selected five...

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...