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973 results found

Chorda tympani in middle ear surgery

This was a prospective study at a single Belgian centre that aimed to monitor postoperative taste problems after middle ear surgery. The authors also looked at the influence of pathology and manipulation of chorda tympani (CT) on its function. Taste...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Risk factors for loco regional recurrence for oral SCC

Over 250,000 cases of oral squamous cell carcinomas are diagnosed annually worldwide with 128,000 registered deaths. The authors of this study are from a single institution in Germany and have conducted a retrospective audit of 517 patients with oral SCC...

Dutch pharyngeal pouch surgery experience

A decade’s experience of pharyngeal pouch surgery was reported in this paper from Rotterdam. A total of 94 patients were analysed. The majority (80%) underwent an endoscopic approach, either with stapling or CO2 laser-assisted. Interestingly, 13 of 75 (14%) procedures...

A comparison of same day with staged bilateral cartilage graft tympanoplasty for tubotympanic CSOM

This randomised, controlled study compares the tympanoplasty outcomes in two groups of patients: one undergoing bilateral tympanoplasty on the same day (18 patients, 36 ears) and the other having the same procedure done on different days, with a gap of...

A comparison of cold dissection, coblation and diode laser tonsillectomy

Excellence in tonsillectomy is based on the time taken, blood loss and rapid recovery with minimal pain. In this study, 120 children underwent tonsillectomy by three methods, namely cold dissection, coblation and diode laser dissection in three randomly allocated groups...

Benefits of combined antiviral and corticosteroid therapy in Bell’s palsy and the role of decompression surgery

Early use of steroids has been established as standard management in Bell’s palsy but simultaneous use of antiviral agents has variable acceptance. This review article analyses statistically based evidence to settle the issue. High quality evidence from a 2009 Cochrane...

Hereditary haemorrhagic telangiectasia

This is a very nicely written overview of this difficult condition by two expert rhinologists with a tertiary practice. The genetic basis, pathophysiology, diagnosis, natural history and available management options are all discussed. Clearly there is a large spectrum of...

Idiopathic sudden sensorineural hearing loss and vertigo

This prospective longitudinal study evaluated vestibular function inpatients with idiopathic sudden sensorineural hearing loss (ISSHL) using caloric and video head impulse tests. All patients were admitted for treatment of their ISSHL and divided into two cohorts depending on presence or...

Facial paralysis risk factors in benign parotid surgery

The literature shows that the risk of facial paralysis following benign parotid surgery can be as high as 57% for temporary weakness and 7% for permanent facial nerve damage. It is generally thought that the factors involved may be related...

Systemic steroids for sensorineural hearing loss

This Japanese retrospective study looked at whether the dosage of prednisolone affects the response rate in patients with idiopathic sudden sensorineural hearing loss. The authors included a total of 159 patients over a 14-year period who were treated with 200mg/day...

Cambodian Children Surgical Centre: a junior’s perspective

The Children’s Surgical Centre (CSC) is a Non-Governmental-Organisation (NGO) hospital situated in Phnom Penh, the capital of Cambodia. CSC was developed for landmine victims over 20 years ago by Dr Jim Gollogly after the dark period under the Pol Pot...