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Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Prominauris: Which surgical technique to use?

Otoplasty accounted for 3.2% of all plastic surgical interventions, and 2.6% worldwide in 2015. Patient satisfaction ranges above 95% for prominent ear correction despite the myriad of available techniques in the literature associated with highly variable outcomes. The authors split...

Global Ambassadors Highlights of the Year

Audiology, Indian Subcontinent, Krishna Yerraguntla Over 466-million people live with disabling hearing loss and global costs of unaddressed hearing loss is 750-billion international dollars. Thus, to alleviate the impact of hearing loss on lives of people, The World Hearing Day...

Asymmetrical hearing loss following prolonged occupational noise exposure

Noise-induced hearing loss (NIHL) is one of the commonest occupational conditions and has been linked with increased risk of work-related injuries. Noise-induced hearing loss is traditionally associated with bilateral symmetrical sensorineural hearing loss unless they are exposed to unilateral noises,...

Does Eustachian tube dysfunction improve with FESS?

This multinational study prospectively collected SNOT-22 data to determine the prevalence and severity of, and whether endoscopic sinus surgery (ESS) had improved, symptoms of Eustachian tube dysfunction in patient with chronic rhinosinusitis (CRS). The SNOT-22 includes two questions which are...

Re-establishing ENT services in Liberia after three decades

Liberia is a country located on the West African coast bordered by Guinea, Sierra Leone and the Ivory Coast. Founded in 1821, it is Africa’s oldest modern republic and was established on land acquired for freed US slaves by the...

Roshna Rose Paul: interview between trainee and senior surgeon

Professor Paul has been heavily involved with training and educating multiple cohorts of ENT trainees over the years, since 2010. In this article, Mr Reid (a current ENT registrar from the West Midlands) picks her brains. Prof Roshna Rose Paul....

Global audiology during COVID-19

The COVID-19 pandemic has affected, and in some areas, put a complete hold on, audiology practice around the world. In April 2020, during the peak of the pandemic for many regions, our audiology Global Ambassadors provided their reports from their...

The Medical Art Society

Historian, sculptor and general polymath Neil Weir neatly demonstrates the strong links between our speciality and the creative arts, along with his colleague from the Medical Art Society, Jeanette Cayley. At a summer meeting of the British Medical Association in...

The Malawi Hearing Project

Rachael Collins, ENT trainee in the UK, and Mwanaisha Jauza Phiri, audiologist in Malawi, explore the challenges and innovations in delivering ear and hearing care (EHC) across Malawi. The Malawi Hearing Project, a partnership between QECH and Cambridge Global Health...

Airway stenting in paediatric ENT

Although experience in the use of airway stents in adults is considerable, their use in children is more recent and more limited. Cláudia Schweiger and Michael J Rutter provide an overview of stents and their use in paediatric airway. Stenting...