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PAI journal cover image.

Recurrent ENT infections in children – is it a sign of primary immunodeficiency disease?

1 January 2019 | | antibody, immunoglobulin, intravenous administration, polysaccharide, primary immunodeficiency diseases, subcutaneous administration
ENT clinicians often come across children with recurrent ear, sinus and pulmonary infections. These recurrent infections, albeit common in childhood, can represent an early sign of primary immunodeficiency diseases (PIDD). PIDD is an underdiagnosed group of genetic disorders involving absent...
PAI journal cover image.

A trial of house dust mite sublingual tablet in children with allergic rhinitis

1 May 2019 | | ENTA - Audiology - Adult, ENTA - Audiology - Auditory Implants, ENTA - Neurotology, ENTA - Otology, ENTA - Tinnitus, ENTA - Vestibular Disorders
The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...
Allergy journal cover image

The polyp shrinker

30 April 2020 | | ENTA - Rhinology / Sinus
Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...
Allergy journal cover image.

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

5 November 2021 | | ENTA - Rhinology / Sinus | chronic rhinosinusitis, dupilumab, mepolizumab, omalizumab, reslizumab
Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

From vision to practice: building person-centred hearing care

3 September 2026 | | ENTA - Audiology - Diagnostic
A five-year systematic approach to person-centred hearing care in China shows how implementation, reflection and learning deepen understanding of the person. Person-centred care (PCC) has become increasingly important in healthcare, including audiology. Although its principles are widely recognised, implementing them...

An audio inclusivity project

31 January 2026
Hackney has become the hub of a new initiative for audio inclusivity, with three of the London borough's leading music venues now boasting state-of-the-art, audio-inclusive acoustics. Audio inclusivity is a concept developed to ensure venues and experiences are accessible and welcoming for people of all hearing abilities, including those who are noise-sensitive.

Thyroid nodules – time for a rational imaging approach

1 May 2014 | | ENTA - Thyroid / Parathyroid Surgery
“The more you know, the harder it is to take decisive action. Once you become informed, you start seeing complexities and shades of gray. You realize that nothing is as clear as it first appears. Ultimately, knowledge is paralyzing.” Calvin,...

Prednisolone and/or acyclovir for Bell’s palsy

5 January 2022 | | ENTA - Head & Neck
Landmark Paper: Sullivan FM, Swan IRC, Donnan PT, et al. Early treatment with prednisolone or acyclovir in Bell’s Palsy. N Engl J Med 2007;357(16):1598-607. Facial nerve paralysis as a consequence of Bell’s palsy can result in devastating long-term effects on...

OBITUARY: Dr David Pothier

1 September 2018
David Pothier passed away on July 27, 2018 in the early hours of the morning following a struggle with recurrent brain cancer. His passing extinguished a brilliant light, the likes of which few of us will witness in our lifetime....

KTP laser in the office

1 March 2016 | | ENTA - Laryngology / Swallowing / Voice
KTP laser surgery offers a new way of selectively targeting microvasculature within laryngeal lesions and leaving normal surrounding tissues like epithelium and lamina propria intact – and thus preserving physiological phonation. This kind of selective photoangiolysis can be performed in...

In conversation with Professor Patrick Gullane: My life in Otolaryngology-Head & Neck Surgery

1 September 2014 | | ENTA - ENT
Fellowship RCSEng 2009. Patrick, as you have recently ‘stepped down’ as Chairman and Chief of ORL-HNS at Toronto General Hospital, what next? Firstly, so often I have been asked why I selected this career path, from a quote by Johnny...

Continuous intraoperative neural monitoring and thyroid surgery

3 September 2026 | | ENTA - Head & Neck, ENTA - Thyroid / Parathyroid Surgery
Continuous intraoperative neural monitoring enhances thyroid surgery safety, helping predict and prevent recurrent laryngeal nerve injury in real time. Recurrent laryngeal nerve (RLN) injury with resultant vocal cord paralysis (VCP) can have a significant impact on patient quality of life...