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Relationship between ART and language development
Assisted Reproduction Technology (ART) and especially more invasive techniques of ART may be associated with an increase in neurodevelopmental problems including language delay. Some studies have reported slightly worse perinatal outcomes of IVF babies compared to naturally conceived babies. The...
Patients with advanced oral cavity carcinoma are not candidates for the ‘organ preservation’ approach
The authors of this study, from the University of Michigan, evaluated the role of induction chemotherapy for patients with stages III and IV resectable oral squamous cell carcinoma. Nineteen patients were initially enrolled in the induction chemotherapy cohort. Patients with...
Thyroid nodule update
This excellent article summarises the current diagnostic difficulties with an endocrine gland that frequently produces nodules, some of which may harbour malignancy. At 50 years of age and over there is about a 50% chance of having a nodule; at...
Malignant craniopharyngiomas
Craniopharyngiomas are successfully managed with surgery and / or adjuvant chemoradiotherapy. The transnasal endoscopic route has become increasingly utilised in the management of these challenging tumours. This paper reviews 23 cases from the literature of the rarely reported malignant transformation....
DIY Epley manoeuvre
This is an interesting paper that looks at getting patients to do their own particle repositioning manoeuvre (PRM) after having it done by a clinician (‘Epley’ to you and me although there are some slight differences) once a week for...
Acoustic schwannoma regression post-Gamma Knife treatment
In this retrospective study the authors studied the optimal interval following radiosurgery for differentiating between true growth of tumour versus pseudoprogression using serial volumetric data. A total of 118 patients with a median tumour volume of 0.74cm3 at Gamma Knife...
Earlier intervention to correct anosmia?
This is an interesting study aimed to determine the timing for successful surgical intervention in improving the sense of smell in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). A total of 86 CRSwNP patients with loss of smell and...
Implications of tonsillectomy in very young children
This is a comprehensive study comprising 157 children who underwent tonsillectomy below the age of two years, mainly for sleep-disordered breathing (86.6%) and recurrent tonsillitis (7%). With relatively recent understanding of OSAS, the indications for tonsillectomy in children under two...
How common is self-reported dysphagia in the general population?
Healthcare policymakers and commissioners of services often review incidence and prevalence data when deciding on resource allocation. The authors of this paper have capitalised on a large dataset, the Canadian Longitudinal Study on Aging (CLSA), which collects data on over...
A comparison between biologic and surgical treatment (FESS) for chronic rhinosinusitis with polyposis
In recent years, it is being increasingly recognised that chronic rhinosinusitis with nasal polyps (CRSwP) is a type 2 chronic inflammation based on IL-4 and IL-13, and the novel monoclonal antibody, such as dupilumab, is likely to have a major...
Are we now safe at work?
Fifty years is a long time, yet the years pass in a blink of an eye. Where are we in comparison to where we were then, in terms of the occupational protection from noise exposure and ototoxicity, other than being...
