Assisted Reproduction Technology (ART) and especially more invasive techniques of ART may be associated with an increase in neurodevelopmental problems including language delay. Some studies have reported slightly worse perinatal outcomes of IVF babies compared to naturally conceived babies. The purpose of this study was to determine the language development in three to 10 year old children born following assisted oocyte activation (AOA). The authors assessed expressive and receptive language development of 20 children with a mean age of 5.4 years. They used the Clinical Evaluation of Language Fundamentals (CELF-IV-NL) for children older than five years and the Reynell Developmental Language Scale (RTOS) for children younger than or equal to five years. They found that the language development of singleton babies was significantly better than that of twins born following AOA. Further long-term follow-up studies in this population are needed to provide information on the language development of children born following ART /AOA.

Language development of children born following intracytoplasmic sperm injection (ICSI) combined with assisted oocyte activation (AOA).
D’haeseleer E, Meerschaut FV, Bettens K, et al.
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Gauri Mankekar

Department of Otolaryngology-Head Neck Surgery, Louisiana State University Shreveport, Louisiana, USA.

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