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Role of copper ions in drinking water in the pathogenesis of oral submucous fibrosis: the missing link in the aetiopathology?
Often a breakthrough link in the understanding of the aetiopathogenesis of a hitherto common pathology that has been evading the medical community may not come from the hi-tech labs of the developed world, but from the intelligent investigations from a...
Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...
Do nasogastric tubes affect aspiration risk?
A nasogastric tube (NGT) is frequently used for patients who are at risk of endotracheal aspiration of oral diet. However, this cannot eliminate the aspiration of saliva. The incidence of aspiration pneumonia in patients with NGT therefore remains high. Some...Giacomo Puccini’s laryngeal cancer
Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...Military otolaryngology and its impact on civilian trauma care
Over the centuries, military conflicts and wars have caused both death and injuries and led to improvements in the care of the combat wounded. Military otolaryngologist-head and neck surgeons have been at the forefront of these developments and advances. War...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...
