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Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...Could social isolation be a factor in the link between hearing loss and dementia?
In 1802, Beethoven wrote to his brothers Carl and Johann about his hearing loss: “You men who think or say that I am malevolent, stubborn, or misanthropic, how greatly do you wrong me. You do not know the secret cause...Anaesthesia for free-flap surgery
Adel Hutchinson is one of those calm and controlled anaesthetists for whom nothing seems too difficult. In this article, she describes the key perioperative factors for one of the highest complexity operations in ENT; free-flap surgery. It makes good reading...
Post-operative tonsillectomy bleeding with a normal clinical exam
Tonsillectomy is amongst the most common surgical procedures performed across the western world. For patients who report bleeding post-tonsillectomy, but have no clinical findings on examination, the management can be unclear. The accepted current management in most centres would be...
Polysolmnography and laryngomalacia severity
Laryngomalacia represents the single most common cause of stridor in infants. Most cases are self-resolving, but a proportion of children will require surgical intervention. This group aimed to analyse the efficacy of polysomnography in determining the severity of laryngomalacia in...
Time to endoscopic sinus surgery and outcomes
A well written prospective study, which demonstrates that patients who require endoscopic sinus surgery, should be operated on without long delay since this achieves better and more sustained outcomes. There were 1493 patients undergoing primary nasal surgery who had completed...
Auditory deprivation and single-sided deafness
In cases of bilateral auditory deprivation, there is clear evidence of an inverse relationship between performance after cochlear implantation and the length of severe to profound deafness prior to implantation (i.e. the longer the deprivation the poorer the outcome on...
Should we be doing earlier MRIs in sudden sensorineural hearing loss?
There is recognised variation between ENT departments in exact imaging protocols for the workup of idiopathic sudden sensorineural hearing loss (ISSNHL) but a routine MRI to exclude retrocochlear pathology is standard, usually following immediate treatment with oral +/- intratympanic steroids....
Does pollution worsen inflammatory nasal problems?
This ambitious study, conducted over a period of four years, assessed 27,863 patients and compared levels of allergic rhinitis (AR) or chronic rhinosinusitis (CRS) with the levels of air pollution recorded, as assessed by levels of particulate matter (PM10). They...A ‘rye’ tail – the fatal illness of Lord Boringdon, a Regency tragedy
The anonymous privately-printed book, Some Account of Lord Boringdon’s Accident, describes in deferential terms a case of aspiration of a foreign body and its sequelae. Today aspirated foreign bodies are serious but curable injuries; before the invention of the bronchoscope...
