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Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

Thyroid cancer – the last decade

Professor Ashok Shaha describes the evolution in the treatment of thyroid cancer that he has witnessed over the last decade and the invaluable progress made by himself and others, from their contributions to staging systems and guidelines. Nuances and paradigm...

Auditory brainstem implant results in adults and children

Background The auditory brainstem implant (ABI) has been developed from cochlear implant (CI) technology and is indicated for people who have anatomical abnormalities of the cochlea or dysfunction of the auditory nerve. The majority of people who have received an...

A psychophysical perspective on single-sided deafness and its treatment by cochlear implants

Bob Carlyon gives us a psychophysical perspective on the hearing benefits that can and cannot be achieved for patients with single-sided deafness with a cochlear implant, and discusses some of the challenges in maximising the effectiveness of the treatment. He...

Hearing rehabilitation after vestibular schwannoma surgery

Hearing rehabilitation is a key focus of the management of patients with vestibular schwannoma. But how do we rehabilitate hearing when the cochlear nerve has been damaged by tumour, irradiation, or resective surgery? Mathieu Trudel, Scott Rutherford and Simon Lloyd...

Balance and vestibular disorders in children

Discover the world of paediatric vestibular assessment and management from the team at Alder Hey Children’s Hospital, which is revolutionising services in this field. Dizziness and balance problems generate significant morbidity in children of all age groups. Vestibular disorders are...

Neuroimaging WG3. Neuroimaging as a window on the heterogeneity of tinnitus

Pim van Dijk and Sven Vanneste describe the hope that brain imaging techniques used for research will provide a better understanding of the heterogeneity of tinnitus through large-scale analysis. Their project will create a procedure whereby researchers can submit their...

Genomic testing for deafness and its implications

Gene therapies for hearing loss are rapidly advancing and will be transitioning to clinical practice. Here, the authors explain why clinicians involved in managing these disorders need to be aware of these advances. Genomic testing in England was significantly reconfigured...

Cochlear implants and therapeutics: a natural partnership?

Global awareness of cochlear implants as a solution for hearing loss is slowly increasing and gaining acceptance. The potential for combining cochlear implants with inner ear therapeutics is immense, with promise in several areas. This article takes us on a...

Hidden hearing loss in humans: cochlear synaptopathy is superseded by cognitive effects when listening to speech in noise

Elizabeth Beach presents an overview of the recent research being undertaken at the National Acoustic Laboratories on speech in noise and its relationship to cochlear synaptopathy. Our team at the National Acoustic Laboratories (NAL) has been investigating hidden hearing loss...

The preventative audiologist

Rob Shepheard has been championing the role of ‘the preventative audiologist’ for many years. In this article, he explores how that can be achieved.