You searched for "CRS"

389 results found

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Olfactory neuronal damage in sinusitis

So many patients with nasal disorders have poor olfactory function, yet sometimes the nose may seem comparatively clear of conductive problems. This study postulated that neuronal damage in the olfactory apparatus would lead to a leakage of neuron specific enolase...

Elevated intracranial pressure versus migraines versus sinusitis?

This narrative review discusses the challenges faced by an otolaryngologist to differentiate elevated intracranial pressure (eICP), migraines and chronic rhinosinusitis (CRS). Facial pain, pressure, aural fullness, muffled hearing and tinnitus are often common symptoms described by patients with all three...

Benefits of bilateral cochlear implants

In an ideal world, if you could increase the clinical use of bilateral cochlear implant (CI) treatment, would you? If you’re interested in exploring the clinical benefits of bilateral CIs, or how reviews can directly inform patient care, this systematic...

In conversation with Professor Claire Hopkins

There can be few ENT surgeons who have had such a pivotal role in the COVID pandemic as Claire Hopkins. She has been instrumental in changing the diagnostic criteria, and has been a frequent presence in the media, as Sean...

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

Review: Cochlear Implantation in SSD?

Contra lateral routing of signals (CROS) using hearing aids and bone conduction devices has been the conventionally accepted modality for the treatment of single sided hearing impairment. The CROS hearing aid has been found to improve speech understanding in noise,...

IFOS Dubai 2023

Hussain Abdul Rahman Al Rand, Msc (Cairo), German Board (Facharzt), FRCS (Edin), President, IFOS World Congress Dubai, 2023; Assistant Under Secretary Public Health, Ministry of Health and Prevention, UAE; Vice President, IFOS; President, ARABFOS, GCC ORL Head and Neck Society,...

Omalizumab for CRSwNP: a monoclonal antibody

A prospective study from London, evaluating the response of chronic rhinosinusitis patients with nasal polyposis who were being treated with monoclonal antibody against IgE for severe allergic asthma. Thirteen patients were treated with Omalizumab, according to UK guidelines for their...

Time to endoscopic sinus surgery and outcomes

A well written prospective study, which demonstrates that patients who require endoscopic sinus surgery, should be operated on without long delay since this achieves better and more sustained outcomes. There were 1493 patients undergoing primary nasal surgery who had completed...

Bone anchored hearing devices in very young children

This paper presents results of BC devices in very young children and helps inform an honest discussion of risks / benefit with prospective parents. The authors of this article from Starship Children’s Hospital, Auckland, New Zealand have a series of...

Updates on current evidence for biologics in chronic rhinosinusitis

For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...